Functional Scientific Researcher

ImagineeerArlington, VA
3dRemote

About The Position

In this role, you will provide scientific expertise in support of Office of Research Innovation, Validation, and Application’s (ORIVA) mission to develop, validate, and apply non-animal approaches and innovative technologies to advance human-centered biomedical research across National Insitutes of Health (NIH). You work directly alongside NIH scientific and program staff across two divisions: D-NICEATM and DAIBR.

Requirements

  • PhD in a biomedical field (toxicology, pharmacology, cell biology, molecular biology, biochemistry, or related) with 1+ years of relevant experience OR Master's degree in an equivalent field with 4 years of additional experience
  • Demonstrated expertise in NAMs or a closely related scientific field
  • Experience developing, evaluating, or validating in vitro or computational methods for human health safety or risk assessment
  • Strong scientific writing and oral communication skills
  • Strong critical thinking, problem-solving, and organizational skills
  • U.S. citizenship required; ability to obtain Public Trust clearance

Nice To Haves

  • Familiarity with 3Rs principles (Replace, Reduce, Refine) and their application in NIH-funded research
  • Prior NIH and/or HHS contractor experience
  • Peer-reviewed publications in NAMS-related field

Responsibilities

  • Evaluate New Approach Methodologies (NAMs) and prepare documentation aligned with guidelines from the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), FDA, EPA, and the Organization for Economic Co-operation and Development (OECD)
  • Design and coordinate interlaboratory validation studies; analyze bioactivity, in vitro/in silico, and dose-response data
  • Contribute to study design and provide expert recommendations on data adequacy for government reports and regulatory submissions
  • Apply and evaluate computational methods for human health safety and risk assessment
  • Review and curate data from relevant scientific databases; perform literature searches in government platforms
  • Draft scientific materials including technical reports, research highlights, and meeting summaries
  • Support scientific meetings including ICCVAM calls, public forums, and national/international conferences
  • Collaborate with NIH scientists, program officers, and cross-functional teams on program deliverables

Benefits

  • 401(k) matching
  • Competitive salary
  • Health insurance
  • Paid time off
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