Field Scientific Director (MSL), Payer and Evidence

Amylyx Pharmaceuticals • Cambridge, MA

13h • Remote

About The Position

The Field Scientific Director, Payer & Evidence is a field-based Medical Affairs role responsible for advancing Amylyx’s Market Access, Health Economics & Outcomes Research (HEOR), and Real-World Evidence (RWE) strategies through engagement with payer decision-makers. The role connects clinical evidence, value demonstration, and market access by translating complex data into insights that support patient access and strategic decision-making.

The position develops and executes territory-level engagement strategies, builds scientific relationships with payer and healthcare decision-makers, presents clinical and economic evidence, and serves as a resource for customer questions. It also works with internal and field-based partners across Market Access, Medical Affairs, Sales, and other teams to coordinate compliant communications, share field insights, and pursue research and value-based care collaborations.

This is a remote position within the United States, with regular meetings at Amylyx’s Cambridge, Massachusetts office. Preference is given to candidates in New England who can attend in person as needed. The role requires travel of more than 70%, including overnight stays as needed. The estimated base salary range is $228,000–$257,000 USD. Eligible employees may also receive annual performance-based bonuses and equity awards, along with a comprehensive benefits package.

Requirements

• Advanced degree in biosciences, such as PharmD, PhD, MD, DNP, or DHSc.
• At least 7 years of experience in a scientific or health-related field-based, customer-facing industry role; payer experience is required.
• Deep understanding of the US healthcare system and value-based decision-makers in private and public payers, IDNs, and other payer-related customers at regional and national levels.
• Expertise in HEOR, RWE, and value assessment, including experience with AMCP Dossiers, FDAMA 114, budget impact, and economic models.
• Experience applying HEOR/RWE research and data analytics to communicate study findings across clinical and HEOR topics.
• Strong scientific communication skills, including the ability to translate and present complex scientific information clearly and compellingly.
• Exceptional interpersonal skills, emotional intelligence, and ability to engage effectively with diverse stakeholders.
• Strong business acumen, knowledge of the healthcare environment and biopharmaceutical industry, and ability to develop, manage, and execute strategic plans.
• Ability to work effectively with cross-functional teams, including Market Access, Clinical, Medical Affairs, and Commercial.
• Ability to build and maintain trust with internal and external stakeholders.
• Resourcefulness, self-motivation, and ability to thrive in an entrepreneurial environment.
• Ability to travel more than 70%, including overnight stays as needed.
• Ability to attend meetings at the Cambridge, Massachusetts office regularly; remote workers must have a work setting that supports privacy, reliable internet, phone access, and video conferencing.

Nice To Haves

• Rare disease experience.
• Field Medical Affairs experience as a medical science liaison.
• Residence on the East Coast near a metropolitan airport.
• Residence in the New England region and ability to attend in person as needed.

Responsibilities

• Engage national, regional, and local healthcare decision-makers on payer initiatives, RWE, HEOR, and clinical or economic barriers to patient access.
• Plan and execute territory-level customer engagement strategies in alignment with Market Access and Medical Affairs strategy.
• Establish and maintain scientific relationships with payer medical directors, pharmacy directors, formulary committee members, IDNs, ACOs, and other healthcare decision-makers.
• Present scientific information to formulary committees and other key healthcare decision-makers, including health economic models and supporting clinical data, and address related questions.
• Maintain a consistent field presence for customer meetings and regional or national conferences as needed.
• Understand payer needs and priorities, develop territory strategic plans, and tailor engagement to individual customers.
• Present clinical, humanistic, and economic evidence and product value propositions clearly and compellingly to payer audiences.
• Develop and implement field HEOR/RWE strategy with internal and field-based Medical and Commercial partners.
• Serve as a trusted resource to customers and share relevant expertise.
• Collaborate with payer decision-makers in the assigned healthcare ecosystem to understand and address informational needs and challenges.
• Explore collaborations on value-based care and research initiatives.
• Gather and communicate payer insights, evidence gaps, and emerging healthcare trends to inform actionable recommendations and medical and commercial strategy.
• Coordinate with field Market Access Account teams, RSDs, Sales, and other field teams to maintain alignment, coordination, and compliant messaging.
• Partner on RWE/HEOR research initiatives and publications.
• Advise payer decision-makers and internal teams on disease states, value-based assessments, healthcare and payer policies, and emerging payer-related topics.
• Monitor emerging science, healthcare-market issues, pricing, and regulatory actions relevant to regional and national payer decision-makers.
• Train and support internal teams on payer and value-based healthcare concepts.

Benefits

• Eligible employees may receive annual performance-based bonuses.
• Eligible employees may receive equity awards.
• Comprehensive benefits package designed to support health, well-being, and financial security.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree