Field Scientific Director (MSL), Payer and Evidence

Amylyx Pharmaceuticals • Cambridge, MA

1d • $228,000 - $257,000 • Remote

About The Position

The Field Scientific Director, Payer & Evidence is a field-based Medical Affairs role responsible for advancing Amylyx’s Market Access, Health Economics & Outcomes Research (HEOR), and Real-World Evidence (RWE) strategies through engagement with payer decision-makers. The role connects clinical evidence, value demonstration, and market access by translating complex data into insights that support patient access and strategic decision-making.

The position works with national, regional, and local healthcare decision-makers, develops territory engagement strategies, and establishes scientific relationships with payer medical and pharmacy directors, formulary committee members, IDNs, ACOs, and other decision-makers. It also collaborates with internal Medical Affairs, Market Access, Commercial, and field teams; contributes payer insights and evidence-gap analysis; and supports HEOR/RWE research initiatives and publications.

This is a remote position within the United States, with regular meetings at Amylyx’s Cambridge, Massachusetts office. Candidates must have a suitable remote work setting and be able to travel more than 70%, including overnight stays as needed. Preference is given to candidates in New England who can attend in person as needed.

The estimated base salary range is $228,000–$257,000 USD. Eligible employees may also receive annual performance-based bonuses and equity awards. Amylyx offers a comprehensive benefits package.

Requirements

• Advanced degree in biosciences, such as PharmD, PhD, MD, DNP, or DHSc.
• At least 7 years of experience in a scientific or health-related field-based, customer-facing industry role; payer experience is required.
• Deep understanding of the US healthcare system and value-based decision-makers in private and public payers, IDNs, and other payer-related customers at regional and national levels.
• Expertise in HEOR, RWE, and value assessment, including experience with AMCP Dossiers, FDAMA 114, budget impact, and economic models.
• Experience applying HEOR/RWE research and data analytics to communicate study findings on clinical and HEOR topics.
• Strong scientific communication skills, including the ability to translate and present complex information clearly and compellingly.
• Exceptional interpersonal skills and emotional intelligence, with the ability to engage diverse stakeholders effectively.
• Strong business acumen, including knowledge of the healthcare environment and biopharmaceutical industry, and the ability to develop, manage, and execute strategic plans.
• Ability to work effectively with cross-functional teams, including Market Access, Clinical, Medical Affairs, and Commercial.
• Ability to build and maintain trust with internal and external stakeholders.
• Resourcefulness, self-motivation, and ability to thrive in an entrepreneurial environment.
• Ability to attend meetings at the Cambridge, MA office on a regular basis.
• Access to a remote work setting that supports role requirements, including privacy, reliable internet, phone, and video conferencing.
• Ability to travel more than 70%, including overnight stays as needed.

Nice To Haves

• Rare disease experience.
• Field Medical Affairs experience as a medical science liaison.
• Residence on the East Coast near a metropolitan airport.
• Residence in the New England region and ability to attend in person as needed.

Responsibilities

• Engage national, regional, and local healthcare decision-makers on payer initiatives, RWE, HEOR, and reducing clinical and economic barriers to patient access.
• Plan and execute territory-level customer engagement strategies aligned with Market Access and Medical Affairs strategy.
• Establish and maintain scientific relationships with payer medical directors, pharmacy directors, formulary committee members, IDNs, ACOs, and other healthcare decision-makers.
• Deliver scientific presentations to formulary committees and other decision-makers, communicating health economic models and supporting clinical data, and respond to related questions as the primary field-based contact.
• Maintain a consistent and productive field presence across the assigned geography, including customer meetings and regional and national conferences as needed.
• Understand payer needs and priorities, customize engagement strategies, and communicate clinical, humanistic, and economic evidence and product value propositions clearly.
• Develop and implement field HEOR/RWE strategy with internal and field-based Medical and Commercial partners to provide a strong customer experience.
• Collaborate with payer decision-makers in the designated healthcare ecosystem to understand informational needs and explore value-based care and research partnerships.
• Gather and communicate payer insights, evidence gaps, and emerging healthcare trends to inform actionable recommendations and medical and commercial strategy.
• Coordinate with field Market Access Account teams, RSDs, Sales, and other field teams to support aligned, consistent, and compliant messaging.
• Partner on RWE/HEOR research initiatives and publications.
• Advise internal teams and payer decision-makers on disease states, value-based assessments, healthcare and payer policies, and emerging payer topics.
• Monitor emerging science, market issues, pricing, and regulatory actions relevant to regional and national payer decision-makers.
• Provide internal training and support on payer and value-based healthcare concepts.

Benefits

• Eligible employees may receive annual performance-based bonuses.
• Eligible employees may receive equity awards.
• Comprehensive benefits package designed to support health, well-being, and financial security.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree