Faculty Position, Center of Excellence in Neuro-Oncology Sciences (CENOS)

St. Jude Children's Research Hospital•Memphis, TN

13d•Onsite

About The Position

St. Jude Children’s Research Hospital invites applications for a research faculty position at the assistant/associate member rank (equivalent to assistant or associate professor) to join the newly established Center of Excellence in Neuro-Oncology Sciences (CENOS). CENOS aims to address foundational biological questions and drive clinically impactful discoveries to advance knowledge and enhance survival outcomes for children with malignant brain tumors. Successful applicants will join a cohort of thriving research groups who study childhood brain tumors from complementary angles. We are seeking an investigator to lead a multidisciplinary research program focused on advancing our understanding of malignant childhood brain tumors through innovative approaches in fundamental biology, neuroscience, neuro-immunology, metabolism, data science, and related disciplines. We welcome candidates with expertise spanning mechanistic and translational research, including the development of human stem cell and organoid models to study mechanisms of tumorigenesis; application of advanced multi-omics technologies to characterize tumor, immune, and metabolic states and discover resistance mechanisms; deployment of cancer neuroscience strategies to study communication networks that promote and maintain malignancy; investigation of neuro-immune interactions and metabolic dependencies that influence tumor initiation, progression, and therapeutic response; evaluation of novel selective dependencies and the mechanisms governing these vulnerabilities; and application of machine learning, artificial intelligence, and other advanced data science methodologies to enhance biological discovery, diagnostics, and treatments for malignant childhood brain tumors. Early career investigators interested in contributing to a culture of excellence at St. Jude are encouraged to apply.

Requirements

Ph.D. and/or M.D. degree
At least three years of relevant postgraduate experience
Demonstrated track record of productivity

Responsibilities

Lead a multidisciplinary research program focused on advancing our understanding of malignant childhood brain tumors through innovative approaches in fundamental biology, neuroscience, neuro-immunology, metabolism, data science, and related disciplines.
Develop human stem cell and organoid models to study mechanisms of tumorigenesis.
Apply advanced multi-omics technologies to characterize tumor, immune, and metabolic states and discover resistance mechanisms.
Deploy cancer neuroscience strategies to study communication networks that promote and maintain malignancy.
Investigate neuro-immune interactions and metabolic dependencies that influence tumor initiation, progression, and therapeutic response.
Evaluate novel selective dependencies and the mechanisms governing these vulnerabilities.
Apply machine learning, artificial intelligence, and other advanced data science methodologies to enhance biological discovery, diagnostics, and treatments for malignant childhood brain tumors.