Faculty Position - Department of Computational Biology
About The Position
The Department of Computational Biology at St. Jude Children's Research Hospital is seeking to fill Assistant/Associate/Full Member (faculty) positions. These roles will focus on advancing pediatric cancer research through computational innovation. Two primary areas of focus are A — Omics Technologies, which involves developing next-generation omics platforms for pediatric biology and diseases, and B — AI in Biomedicine, which aims to build foundation models and agentic AI tools for pediatric precision medicine. The department offers a highly collaborative research environment with extensive resources, including cloud computing, high-performance computing, a genomics laboratory, wet lab support, and a software engineering team. The position is key in several institutional projects such as the Pediatric Cancer Genome Project (PCGP) and St. Jude Cloud.
Requirements
- PhD (or equivalent) with at least three years of relevant postgraduate experience, or a demonstrated track record of developing novel, high impact computational methods.
- For Area A: evidence of assay–algorithm co design in RNA/CRISPR/single cell/spatial/metabolomics.
- For Area B: experience with foundation models, multimodal learning, clinical NLP, and trustworthy AI; familiarity with clinical informatics.
Nice To Haves
- Experience building LLM driven, agentic systems for automated analysis or experiment planning with appropriate guardrails is highly valued.
Responsibilities
- Develop next generation omics platforms for pediatric biology and diseases.
- Pioneer assay–algorithm co design.
- Demonstrate cross disciplinary leadership.
- Lead reproducible & open science initiatives.
- Build foundation models and agentic AI tools spanning DNA/RNA/protein/imaging/spatial/EHR data for pediatric precision medicine.
- Develop trustworthy AI (calibration, uncertainty, drift monitoring).
- Build LLM driven, agentic systems for automated analysis or experiment planning with appropriate guardrails.
Benefits
- Generous startup funds
- Computing resources
- Equipment
- Laboratory space
- Personnel support
- Potential institutional support beyond the start up phase
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
