Executive Director, US Market Access

Mirum PharmaceuticalsFoster City, CA
$295,000 - $330,000Hybrid

About The Position

Mirum Pharmaceuticals is a rare disease company with a growing portfolio of innovative therapies and a robust pipeline, Mirum is committed to improving the lives of patients who often face limited treatment options and complex care journeys. We operate with a deep sense of purpose and urgency—grounded in our values: Care. Have Fun. Be Real. Get it Done. As we continue to scale, market access plays a critical role in ensuring that innovation translates into real-world patient access. The Executive Director of Market Access Strategy and Pricing will lead all U.S. Market Access strategy efforts, establishing the long-term vision for pricing, reimbursement, and payor strategy across the entire portfolio of Mirum’s current and future assets. This role demands a proven leader who’s capable of working in highly cross functional teams and can maintain an enterprise mindset while partnering across Commercial, Medical, Patient Services, Finance/Accounting, Legal/Compliance, and Supply Chain to shape and deliver meaningful access strategies. The ideal candidate blends strategic vision with operational experience, bringing deep payer expertise and a passion for rare disease patients.

Requirements

  • Bachelor’s degree required; MBA or advanced financial degree preferred
  • 15+ years of experience in market access, payer marketing, or reimbursement, with rare disease experience strongly preferred
  • Proven success in launching and optimizing access for specialty/rare disease therapies, including pricing strategy
  • Experience in translating complex payer and policy changes into actionable commercial strategies, including MFN and IRA
  • Deep understanding of:
  • Successful experience in leading and developing a team within the market access function
  • Demonstrated ability to lead cross-functional teams and influence senior leadership in small biotech/rare disease companies with agile working environments a plus
  • Strong analytical, strategic, and communication skills
  • Resilient and adaptable and proven experience in navigating complex payer dynamics with confidence

Responsibilities

  • Strategic lead for all payor strategy development resulting in coverage expansion, policy optimization, and quality of access (QOA) improvements across commercial and government payers for inline and pipeline assets.
  • Lead, mentor and build a high-performing team of market access strategy and pricing professionals, championing a culture that represents Mirum’s values.
  • Serves as a strategic advisor to executive leadership, influencing portfolio investment decisions, launch sequencing, business development evaluations, and long-range corporate strategy through the lens of market access and payer dynamics.
  • Anticipates future healthcare policy, reimbursement, and competitive changes, proactively positioning the organization to mitigate risk while identifying new opportunities for growth and patient access.
  • Champions an integrated market access strategy by aligning Medical, Marketing, Med Affairs, Commercial Operations, Commercial Analytics, Patient Services and Payer Accounts.
  • Represents the company externally with executive presence at industry forums, advisory boards, and strategic partner engagements, elevating the organization's leadership in market access innovation.
  • Proactively and regularly collaborates with the US Head of Payer Accounts and the Head of Patient Services on strategic account planning and escalation for high-impact access challenges.
  • Ensures compliance with all regulatory and legal requirements, including government price reporting, 340B ceiling prices and all government calculation requirements.
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