Executive Director, Head of US Rare Endocrinology and Rare Tumors

AstraZeneca • Boston, MA

3d • $282,046 - $423,070 • Hybrid

About The Position

The Executive Director, Head of US Rare Endocrinology and Rare Tumors will provide senior medical leadership and full US Medical Affairs strategic ownership for all in-country Medical Affairs activities for Alexion's Rare Endocrinology and Rare Tumors portfolio. This leader will define and implement the portfolio-wide US Medical Affairs strategy across marketed products, pipeline assets, launch readiness, indication expansion, and lifecycle management initiatives, ensuring alignment with Global Medical Affairs strategy, US business priorities, and patient-centered objectives.

Requirements

• Advanced scientific or clinical degree, including M.D., PharmD, Ph.D., or equivalent advanced degree.
• Minimum of 12+ years of biopharmaceutical industry experience, with significant Medical Affairs leadership responsibility.
• Minimum of 10+ years leading and managing teams, including Medical Affairs organizations.
• Demonstrated experience developing and implementing medical strategy across multiple assets, indications, or stages of the product lifecycle, including marketed and pipeline assets.
• Rare disease experience, with endocrinology, oncology, rare tumors, or related therapeutic area experience strongly preferred.
• Demonstrated ability to influence senior leaders, external experts, and cross-functional partners while advancing medical strategies that improve patient care and outcomes.
• Demonstrated ability to employ digital, data, and AI-enabled capabilities to improve organizational effectiveness, accelerate decision making, and enhance Medical Affairs impact.

Nice To Haves

• Product lifecycle management, launch readiness, and indication expansion experience.
• Experience in early and late clinical development, evidence generation, real-world evidence, and/or investigator-sponsored research.
• Experience representing a therapeutic area in senior leadership forums, global governance discussions, major congresses, professional societies, advocacy engagements, or external scientific forums.
• Experience leading Medical Affairs strategy in a rare disease portfolio with small patient populations, complex diagnostic pathways, and specialized centers of excellence.

Responsibilities

• Advance understanding of the US Rare Endocrinology and Rare Tumors medical and treatment landscape, including evolving standards of care, unmet patient needs, evidence gaps, external expert perspectives, and emerging scientific developments, to inform the development and implementation of appropriate US Medical Affairs strategies aligned with Global Medical Affairs priorities.
• Lead the design and execution of the strategy and tactical plans for assigned tumors, aligned with Global strategy and US priorities.
• Serve as the senior US medical leader for the therapeutic area, including representation in US leadership forums, global governance discussions, and cross-functional portfolio planning.
• Lead and develop a high-performing Medical Affairs team, including Medical Directors, Regional MSL Directors, Medical Science Liaisons, and other therapeutic area team members as applicable.
• Define portfolio priorities, resource needs, and budget planning across the Tumor areas, ensuring trade-off decisions are clearly linked to patient impact, evidence gaps, launch priorities, and business-critical achievements.
• Partner closely with Commercial, Market Access, HEOR, Regulatory, Clinical Development, Medical Operations, Patient Advocacy, and Global Medical Affairs to ensure cross-functional alignment and combined planning activities.
• Provide leadership for launch readiness, lifecycle management, and evidence generation activities, including identification of data gaps and prioritization of real-world evidence, investigator-sponsored research, and company-sponsored research opportunities.
• Lead monthly and quarterly reviews of US Medical Affairs activities, including field medical performance, medical insights, evidence generation progress, and tactical plan execution.
• Ensure timely and high-quality publication planning and medical communication activities in support of Global and US Medical Affairs strategy.
• Drive scientific exchange strategy, advisory boards, congress engagement, thought leader development, and external expert engagement across relevant rare disease communities.
• Collaborate with HEOR and other partners to translate medical insights and evidence gaps into strategic actions that support improved patient care and outcomes.
• Partner with Global Medical Education and internal scientific training teams to localize and develop medical content for field medical scientific exchange and cross-functional education.
• Ensure medically accurate, scientifically balanced, compliant content review processes for promotional and non-promotional materials, as appropriate for the role.
• Drive the strategic adoption of AI and digital innovation within the Rare Endocrinology and Rare Tumors Medical Affairs organization.
• Identify training and development needs in collaboration with key partners and ensure implementation of medical training programs for field medical teams and other team members as appropriate.

Benefits

• short-term incentive bonus opportunity
• equity-based long-term incentive program
• qualified retirement program [401(k) plan]
• paid vacation and holidays
• paid leaves
• health benefits including medical, prescription drug, dental, and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Education Level: Ph.D. or professional degree