Executive Director, Global Commercial Proleukin

Iovance Biotherapeutics

3d•$300,000 - $325,000•Remote

About The Position

Iovance Biotherapeutics, Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com. Amtagvi® and its accompanying design marks, Proleukin®, Iovance®, and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners. Information on Iovance’s broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com. Overview The Executive Director, Global Commercial Proleukin leads the global Proleukin business and sets its long-range strategy and operating priorities for the United States and international markets, including licensed and unlicensed countries. The role is accountable for business performance and coordinates commercial plans with Clinical, Regulatory, Manufacturing, Medical Affairs, Market Access, Sales, Legal, Finance, Supply Chain, and regional teams to support growth, customer needs, reliable supply, and compliance. The Executive Director advises senior leaders on business results, major risks, spending priorities, and growth opportunities and represents Proleukin in leadership reviews and decision-making forums. The role requires sound judgment in a highly regulated environment, strong scientific knowledge, and a clear understanding of the market for oncology therapies, including hospital-administered products. The Executive Director also determines staffing needs, develops leaders, supports succession planning, and sets clear expectations for team performance and collaboration.

Requirements

Bachelor’s degree required
Fifteen or more years of increasing commercial leadership responsibility in the pharmaceutical or biotechnology industry, including experience with complex businesses, global or multi-market plans, financial results, and cross-functional teams
Experience leading a business unit, established brand, global portfolio, or similarly complex commercial operation with direct financial responsibility
Experience with hospital-administered drugs and/or oncology products
Strong knowledge of market access, reimbursement, distribution, inventory management, and customer needs for complex therapies
Experience leading office-based, field-based, cross-functional, and external partner teams, including teams that do not report directly to the role
Excellent written, verbal, presentation, and senior-level communication skills
Ability to interpret complex business and financial information and make clear recommendations to senior leaders
Commitment to integrity, inclusion, sound judgment, and compliance

Nice To Haves

Master’s degree preferred
U.S. and global market experience preferred

Responsibilities

Set and communicate the global commercial strategy, priorities, and performance measures for Proleukin
Own profit-and-loss performance and advise senior leaders on business results, spending priorities, risks, and growth opportunities
Make decisions on inventory, distribution, market priorities, budgets, staffing, and business risks
Own annual and quarterly revenue forecasts, expense budgets, planning assumptions, and spending recommendations
Oversee distribution and inventory to meet demand, manage cost, and maintain supply
Set performance measures and use customer data and business analysis to guide decisions and address performance issues
Lead global business and customer planning, including account coverage, customer groups, distribution, forecasting, and short- and long-range plans
Coordinate commercial strategy with Clinical, Regulatory, Medical Affairs, Market Access, Sales, Legal, Finance, Manufacturing, Supply Chain, and regional teams and represent the business in leadership reviews and strategic planning meetings
Partner with the Vice President of Sales to align commercial strategy, field priorities, training, and performance expectations
Partner with U.S. and Global Market Access leaders to plan for reimbursement changes and address barriers to patient access
Set direction and approve marketing plans and materials, ensuring they support the brand strategy and meet compliance requirements
Lead annual and long-range commercial planning, including key choices, budget recommendations, planning assumptions, and business reviews
Assess and recommend product lifecycle, access, distribution, partnership, and business development opportunities
Guide engagement with clinicians, providers, payers, patient advocates, and other external groups
Guide advocacy, policy, and patient support plans in line with business, access, and compliance requirements
Determine team structure and staffing needs, develop leaders, support succession planning, and hold teams accountable for results
Oversee external partners and ensure their work meets quality, cost, timing, and business requirements
Identify and address commercial, operational, financial, supply, legal, regulatory, medical, privacy, and promotional risks
Follow Iovance Biotherapeutics’ values, policies, procedures, ethics standards, and compliance requirements