DMPK Consultant

Edison Scientific

1d • $100 - $250 • Remote

About The Position

Edison Scientific is seeking an experienced DMPK Specialist for a flexible, part-time consulting engagement. The role involves serving as a subject matter expert on the scientific integrity of AI-generated DMPK outputs, including PK analyses, ADME interpretations, human dose projections, and IND DMPK report sections. The expert's input will directly influence the training and validation of the AI platform and potentially impact the broader practice of DMPK in the AI industry. This engagement is designed to be flexible, as-needed, part-time, with no fixed schedule or rigid hour requirements, allowing it to fit around existing commitments.

Requirements

• 10+ years of hands-on DMPK experience supporting programs from discovery through IND, or direct ownership of 10+ IND-reaching programs
• Proven ability to translate CRO bioanalytical data, in vitro ADME results, and in vivo PK study reports into FDA-ready IND DMPK submissions
• Strong proficiency in PK modeling, with experience in at least one PBPK platform (Simcyp, GastroPlus, or PK-Sim)
• End-to-end ADME fluency
• Comfortable working independently as the primary DMPK voice in an advisory capacity
• Enthusiastic about working with AI/LLM tools to evaluate and improve scientific outputs

Nice To Haves

• Experience with regulatory DDI strategy, including PBPK-based DDI predictions submitted to FDA/EMA
• PK/PD modeling or quantitative systems pharmacology (QSP) experience
• Prior AI/ML work applied to DMPK or ADME property prediction
• Background at big pharma or CROs supporting large pharma IND programs

Responsibilities

• Advise on the development of high-quality DMPK training data spanning the discovery-to-IND workflow — including in vitro ADME panels, in vivo PK across preclinical species, metabolite identification, NCA outputs, and PBPK/population PK simulations
• Provide guidance on optimal data sources, including synthetic generation, consortia, licensed datasets, and public PK/ADME databases
• Review and validate AI-generated DMPK outputs — PK parameter estimates, model fits, ADME interpretations, dose projections, and written report sections — for scientific accuracy and regulatory compliance
• Collaborate with our Engineering, Evals, and Science teams to benchmark agent performance against gold-standard DMPK workflows
• Provide expert input to help refine agent logic, data quality, and overall platform capabilities

What This Job Offers

• Job Type: Part-time
• Career Level: Senior
• Education Level: No Education Listed