Director, Translational Sciences

Incyte Corporation • Wilmington, DE

1d

About The Position

A global biopharmaceutical company on a mission to Solve On, Incyte follows science to find solutions for patients with unmet medical needs. Through the discovery, development, and commercialization of proprietary therapeutics, Incyte has established a portfolio of first-in-class medicines for patients and a strong pipeline of products in Hematology, Oncology and Inflammation and Autoimmunity
Headquartered in Wilmington, Delaware, Incyte has operations in North America, Europe, and Asia.
Job Summary (Primary Function):
The Director, Translational Sciences will lead a hematology and blood coagulation disease program. This is a high-impact leadership role that requires the development of biomarker strategies and translational research for use in ongoing human clinical studies related to a novel treatment for congenital bleeding disorders. The position will collaborate actively with industry and academic partners to investigate the potential utility of this novel treatment as a universal hemostatic therapy for numerous bleeding disorders. Ideal candidates are scientists who thrives at the interface of preclinical biology, clinical development, and biomarker strategy — translating mechanistic insight into first-in-human and later-stage clinical trials.

Requirements

• Exceptional verbal and written communication skills.
• High level of emotional intelligence and willingness to work collaboratively with diverse functional groups, both internal and external to the company.
• Interest in working in and creating an environment of scientific curiosity and open exchange of ideas.
• Ability to balance execution and prioritize multiple tasks to accomplish program goals.
• Passion for exploration of human biology and the development of methods to study disease biology and treatment-associated biological changes.
• Dynamic and innovative scientist.
• Strong scientific background with an advanced degree, such as MD, PhD, or equivalent, and a demonstrated track record of performing excellent science.

Responsibilities

• Lead translational strategy for one or more hematology/coagulation programs, from early discovery through clinical proof-of-concept and beyond.
• Design and oversee biomarker strategies tailored to coagulation cascade biology and bleeding/thrombotic risk assessment.
• Provide ongoing data review, analysis, interpretation, and documentation required to impact key clinical development decisions.
• Partner closely with clinical partners to translate clinical and nonclinical translational findings into clinically actionable trial designs.
• Provide scientific and strategic input on companion diagnostic development where relevant.
• Represent Translational Science in regulatory interactions, including IND/CTA-enabling packages and end-of-Phase meetings, where required.
• Mentor and provide scientific leadership to scientists across the Translational Sciences organization.
• Author and review key scientific documents, including investigator brochures, protocol synopses, regulatory briefing documents, and publications.

What This Job Offers

• Job Type: Full-time
• Career Level: Director