Director, Translational Medicine, Imaging
About The Position
BlueRock Therapeutics is a leading engineered cell therapy company using its unique CELL+GENE™ platform to develop, manufacture, and deliver a new generation of cellular medicines for neurological, cardiovascular, and immunology diseases. The Director of Imaging and Biomarkers, Translational Medicine, will manage imaging protocols and biomarkers in clinical development programs, leveraging expertise in CNS, ophthalmic, and inflammation imaging to advance the company’s development pipeline. This is a highly visible role with internal and external stakeholders, based in Cambridge, Massachusetts.
Requirements
- PhD, MD, PharmD, or equivalent degree in Neuroscience, Biomedical Imaging, Radiology, or related discipline.
- 6+ years of industry experience in translational medicine, imaging sciences, or clinical development
- Deep expertise in clinical and translational neuroimaging, including MRI and PET methodologies
- Must have direct experience managing imaging protocols in the conduct of clinical trials (endpoints, inter-site harmonization, imaging core lab oversight, etc.).
- Specific experience with imaging endpoints for early-stage clinical development in CNS, ophthalmic and inflammatory diseases is desired.
Responsibilities
- Develop translational strategies designed to support clinical development plans, the regulatory path, and product commercialization.
- Lead the development and implementation of translational imaging strategies in support of clinical proof-of-mechanism, patient stratification, and dose selection.
- Serve as the neuroimaging lead on cross-functional program teams.
- Partner with Research to discover and characterize novel imaging biomarkers in preclinical studies.
- Develop imaging methods and analytically validate imaging tools for clinical use.
- Implement clinical biomarkers and ensure biomarker-driven decision-making across all phases of drug development.
- Lead cross-functional imaging governance (e.g., Imaging Steering Committee) advancing the use of imaging biomarkers to enable demonstration of disease-modifying effects.
- Deliver subject matter expertise with respect to clinically advanced techniques in MRI, PET, SPECT, HRCT and other modalities as needed.
- Oversee CRO vendor/partners ensuring that they optimally execute clinical and preclinical imaging projects in the US, Canada, and other regions of interest.
- Provide support for the Business Development organizations as needed on diligence efforts.
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What This Job Offers
Job Type
Full-time
Career Level
Director
Education Level
Ph.D. or professional degree
