Director, Screening and High Content Analysis
About The Position
As the Director, Screening and High Content Analysis, you will lead the development and execution of NGNRI’s high-content screening platform, driving target discovery and therapeutic development using advanced organoid and cell-based models. This role will design and scale automated screening workflows that integrate high-content imaging, quantitative image analysis, and data science approaches, including AI-driven methods. As a scientific and technical leader, you will ensure seamless integration of screening capabilities with NGNRI’s broader research platforms and strategic priorities. This is a key leadership position with a clear mandate: to build and manage robust, high throughput screening and analysis systems that accelerate the discovery of therapeutic targets and compounds for NF1 and related neurological disorders.
Requirements
- High integrity and commitment to scientific excellence
- Innovative and technology-driven mindset
- Strong leadership and team development skills
- Collaborative and interdisciplinary approach
- Detail-oriented with strong organizational skills
- Adaptable and results-driven
- Significant experience in high-content imaging, phenotypic screening, or related fields
- Proven track record in designing and executing automated screening campaigns
- Expertise in image analysis tools and platforms (e.g., CellProfiler, ImageJ, Python based pipelines, or equivalent)
- Experience working with complex biological systems such as organoids or stem cell derived models is a strong asset
- Demonstrated leadership experience in academic, biotech, or pharmaceutical environments
- Strong analytical and problem-solving skills
- Excellent communication and cross-functional collaboration abilities
- Experience managing large datasets and computational workflows
- PhD in bioengineering, computational biology, neuroscience, cell biology, or related discipline
Nice To Haves
- Experience with AI/ML approaches applied to biological imaging data is highly desirable
- Familiarity with drug discovery pipelines is advantageous
Responsibilities
- Establish and lead NGNRI’s high-content imaging and screening platform
- Design and implement automated screening workflows for organoid and cell-based assays
- Develop and optimize imaging assays, phenotypic readouts, and quantitative analysis pipelines
- Integrate AI/ML-based approaches for image analysis and pattern recognition
- Ensure scalability, robustness, and reproducibility of screening pipelines
- Collaborate closely with the Head of Cell Culture and Organoids to align biological models with screening requirements
- Recruit, train, and manage a multidisciplinary team (biologists, imaging scientists, data analysts)
- Oversee data management, storage, and analysis pipelines, ensuring accessibility and integrity
- Partner with internal and external researchers to design screening campaigns for target identification and drug discovery
- Continuously evaluate emerging technologies in imaging, automation, and computational analysis
- Contribute to interpretation of screening results and downstream validation strategies
- Ensure compliance with relevant regulatory, data governance, and ethical standards
Benefits
- Perks and health benefits that will help you have peace of mind
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What This Job Offers
Job Type
Full-time
Career Level
Director
Education Level
Ph.D. or professional degree
