Director, Portfolio Management

Sarah Cannon Research InstituteWork at Home - Tennessee, USA (WTNA), TN
Remote

About The Position

As Director, Portfolio Management, you will lead the strategy, execution, and success of a complex, multi‑study clinical research portfolio—playing a pivotal role in advancing clinical trials that matter. This is a senior leadership position for someone who thrives at the intersection of strategy, operations, and partnership and wants to make a visible impact on sponsors, teams, and patients. You will provide end‑to‑end portfolio leadership across the clinical trial lifecycle, ensuring consistent, high‑quality delivery while driving growth, innovation, and operational excellence. This is a fully remote position based in the US; relocation assistance and visa sponsorship are not available.

Requirements

  • Bachelor’s Degree required
  • 7+ years’ experience in clinical research or project management
  • Prior people leadership including line management
  • Minimum 2 years’ experience in an Associate Director or equivalent role managing multiple complex clinical studies concurrently
  • Demonstrated experience managing clinical trials independently

Nice To Haves

  • Master’s Degree preferred
  • 10+ years’ clinical research experience
  • Medical Affairs experience, including cross-functional engagement and evidence-generation support
  • Pharma/CRO management experience
  • Experience supporting Investigator-Initiated Trials (IITs) including feasibility, start-up coordination, oversight and stakeholder alignment.

Responsibilities

  • Set the direction for a diverse clinical portfolio, translating strategic priorities into clear, executable plans.
  • Ensure strong governance, proactive risk management, and disciplined execution across studies with oversight of scope, timelines, resourcing, quality, and financial performance.
  • Serve as a trusted senior partner to sponsors—leading governance, communications, and issue resolution while strengthening long‑term relationships.
  • Collaborate with Business Development and Clinical Development teams to support proposals, expand partnerships, and grow the portfolio.
  • Establish and sustain a strong operational rhythm that delivers visibility, accountability, and results.
  • Oversee financial performance, risk and issue escalation, and continuous improvement efforts as owner of portfolio‑level KPIs.
  • Coach and develop high‑performing teams, foster talent growth, and serve as a key escalation point for complex delivery and client challenges.

Benefits

  • Comprehensive benefits to support physical, mental, and financial well-being
  • Competitive compensation package
  • Annual bonus or long-term incentive opportunities may be offered
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