Director, Marketing – MPS I and ASMD

Sanofi•Cambridge, MA

1d•$178,500 - $257,833•Hybrid

About The Position

The Director, Marketing – MPS I and ASMD is the brand strategy lead for Sanofi's ASMD and MPS I disease portfolio, encompassing Xenpozyme® (olipudase alfa) for Acid Sphingomyelinase Deficiency (ASMD) and Aldurazyme® (laronidase) for Mucopolysaccharidosis I (MPS I). This role owns brand strategy, campaign and messaging platform, brand planning process, and core team governance for these two disease areas, and serves as the primary U.S.-to-Global commercial partner for both brands. The Director directly manages and develops a team of three — a Patient Experience Marketer, an HCP Experience Marketer, and a PharmD Fellow bringing strong people leadership, strategic thinking, and rare disease commercial expertise to the role. A defining priority of this position is leading the transition of both the ASMD and MPS I brand away from traditional agency-dependent models toward a fully AI/digital marketing platform. This includes building internal digital capabilities, owning content and campaign production digitally, and systematically reducing reliance on external creative and media agencies over time — positioning this portfolio as a model for digital-first, agile brand marketing within Sanofi Rare Disease. Join the team transforming care for people with immune challenges, rare diseases, cancers, and Specialty Care neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs.

Requirements

Bachelor's degree required
Demonstrated ability to lead, coach, and develop direct reports in a fast-paced, complex environment
Strong track record of leading brand planning processes and developing brand campaign strategies
Strong analytics
Proven ability to partner effectively with Global brand teams across geographies and functions
Excellent cross-functional collaboration, communication, and executive presentation skills

Nice To Haves

MBA or advanced degree strongly preferred
Experience managing multiple brands or indications simultaneously preferred

Responsibilities

Own the U.S. brand strategy for Xenpozyme and Aldurazyme, ensuring each brand maintains compelling, differentiated, and commercially sound strategic positioning
Develop and maintain the strategic framework for the ASMD and MPS I portfolio, including portfolio prioritization, lifecycle management, and competitive response strategies
Ensure brand strategies are grounded in data, customer insights, competitive intelligence, and clinical data, addressing the full patient journey
Anticipate market dynamics and proactively evolve brand positioning to reflect the evolving ASMD and MPS I treatment landscapes
Own the brand campaign and messaging platform for ASMD and MPS I, ensuring compelling, differentiated, and compliant brand narratives for both HCP and patient audiences
Lead the development and evolution core messaging, visual identity, and campaign architecture for Xenpozyme and Aldurazyme
Drive the transition to a no-agency, fully in-house digital marketing model, building internal digital production capabilities, establishing in-house content creation workflows, and architecting a digital-first campaign infrastructure
Ensure campaign and messaging alignment across all digital channels and tactics, leveraging internal teams to execute with speed and precision
Champion a culture of digital innovation, testing, and optimization across the ASMD and MPS I brand teams
Lead the annual brand planning process for the ASMD and MPS I portfolio, including situation analysis, strategic imperatives, tactical planning, and resource allocation
Integrate digital transformation milestones and in-house capability-building objectives into annual brand plans
Present brand plans to senior leadership, including the Head Rare/xLSD Marketing and cross-functional leadership, with clear strategic rationale and measurable outcomes
Ensure brand plans reflect the needs of rare disease patients and caregivers, consistent with Sanofi's mission-driven approach to rare diseases
Directly manage and develop a team of three direct reports: Patient Experience Marketer, HCP Experience Marketer, and PharmD Fellow
Set individual goals aligned to brand priorities and the digital transformation agenda; provide ongoing coaching, feedback, and career development support
Foster a team culture grounded in digital innovation, agility, patient-centricity, and continuous learning
Serve as a visible and accessible people leader who models Sanofi's values and commitment to rare disease patients
Lead core team governance for the ASMD and MPS I brands, chairing or co-chairing core team meetings and ensuring cross-functional alignment on brand strategy and execution
Drive accountability for brand plan execution across the core team, tracking milestones and escalating issues as needed
Ensure governance processes support the pace and agility required by the in-house digital marketing model
Serve as the commercial forecasting and KPI development partner for the ASMD and MPS I portfolio, working closely with Finance, GTMC, and the Head Rare/xLSD Marketing
Develop and track brand KPIs, including digital engagement and performance metrics as the marketing platform transitions in-house
Monitor performance against forecast and provide regular, data-driven updates to leadership
Use KPI insights to inform brand strategy adjustments and optimize resource allocation
Serve as the primary U.S. commercial partner to the Global ASMD and MPS I brand teams, ensuring alignment between U.S. execution and global brand strategy
Represent the U.S. commercial perspective in global brand forums and contribute to global brand planning processes
Ensure that U.S. digital-first and in-house marketing innovations are shared with and inform global brand thinking where appropriate