Director, IT Business Partner — G&A and Finance Systems

Definium Therapeutics • San Diego, CA

2d • $203,632 - $233,500

About The Position

Definium Therapeutics is a late-stage clinical biopharmaceutical company focused on developing accessible treatments that unlock healing at scale by applying scientific rigor to psychedelics. Our mission is to forge a new era of psychiatry. Our lead product candidate, lysergide tartrate, is a differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early-stage pipeline includes DT402, the R-enantiomer of MDMA, targeting core symptoms of autism spectrum disorder. We are advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders, aiming to change the trajectory of the mental health care crisis. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX. We are moving psychiatry forward—beyond better, into a boundless future.

The Director, IT Business Partner — G&A & Finance Systems is the single accountable IT owner for Definium’s general & administrative (G&A) and finance application portfolio. This role serves as the primary bridge between Enterprise Technology and the Finance, Accounting, Procurement, People (HR), and in-scope R&D / Clinical functions. The role has two responsibilities of company-wide significance: producing the IT control evidence underpinning Definium’s Sarbanes-Oxley (SOX) program, and serving as the IT operational lead for the governed roll-out of artificial intelligence (AI) across the company.

Requirements

• Bachelor’s degree in Information Systems, Finance, Accounting, Business, or a related field; equivalent experience considered.
• 8+ years of progressive experience administering and delivering enterprise / financial systems, including hands-on ownership of a cloud ERP (NetSuite strongly preferred).
• Demonstrated experience operating and evidencing ITGCs in a SOX environment at a publicly-traded company.
• Working knowledge of procure-to-pay (Coupa), travel & expense (Concur), and HRIS (BambooHR), or comparable platforms.
• Proven project management across full system-implementation lifecycles (including MSP and vendor management), with a strong command of SoD, least-privilege, and change-management disciplines and excellent stakeholder and executive communication skills.

Nice To Haves

• Life sciences, pharmaceutical, biotech, or other regulated-industry experience, including familiarity with GxP, 21 CFR Part 11, and EMA Annex 11, and hands-on Veeva administration (Clinical, Regulatory, Quality suites).
• Experience supporting a pre-commercial company through commercial launch and rapid scaling, and leading enterprise AI enablement within a governance framework.
• Relevant certifications (e.g., NetSuite Administrator / SuiteFoundation, PMP, CISA).

Responsibilities

• Serve as the primary IT business partner to Finance, Accounting, FP&A, Procurement, and People / HR — translating functional needs into a prioritized, business-aligned roadmap and advising on process improvement and automation
• Own administration, configuration, and lifecycle management of the G&A / finance portfolio: NetSuite (ERP), Coupa (procure-to-pay), SAP Concur (T&E), BambooHR (HRIS), Greenhouse (ATS), Malbek (CLM), in-scope Veeva applications, and any newly identified applications as needed
• Manage role design, user provisioning / deprovisioning, integrations, and data integrity under segregation-of-duties (SoD) and least-privilege principles; lead the migration of clinical systems from Medidata to Veeva eTMF / CTMS with the validation resource; and maintain configuration baselines and SOPs
• Lead end-to-end delivery of new G&A / finance systems and enhancements — requirements, vendor selection, implementation, user-acceptance testing, go-live, and hypercare
• Direct the Managed Service Providers (MSPs) and vendors performing build, configuration, and maintenance; manage statements of work, service levels, and escalations; and verify deliverables, including validation where applicable
• Design, operate, and evidence IT general controls (ITGCs) — access management, change management, and IT operations — over financially-significant systems
• Produce the IT control evidence supporting management’s assessment of internal control over financial reporting under SOX Section 404(a) for FY2026–FY2027, and prepare and dry-run the ITGC evidence for the first external-auditor attestation under 404(b) (built through FY2027 ahead of the FY2028 audit)
• Execute periodic user-access reviews, SoD-conflict monitoring, and remediation tracking, partnering with Finance, Internal Audit, and external auditors as the IT control owner and evidence provider
• Enforce access governance, SoD, and least-privilege in partnership with Information Security; support incident response; and ensure systems handling employee and financial personal data (e.g., BambooHR, Concur) are managed in line with applicable privacy laws (e.g., CCPA / CPRA)
• Anticipate the system, control, and capacity needs of a rapidly scaling, soon-to-be-commercial organization; drive automation and integration; and maintain a centralized inventory of SaaS applications, licenses, and entitlements to eliminate redundant or dormant spend
• Serve as the IT operational lead for the safe, governed roll-out of AI across the entire company (not limited to G&A and Finance), executing under the authority and risk framework of Definium’s AI Oversight Group (AOG)
• Operationalize AOG decisions — use-case intake and triage, tooling enablement, access and usage controls, monitoring, and user enablement — partnering with Legal, Quality, Compliance, Information Security, and the Data Protection Officer; escalate product-embedded AI / SaMD questions to the appropriate product-governance pathway

Benefits

• 100% paid health benefits including Medical, Dental and Vision for you and your dependents
• 401(k) program with company match and vesting after the turn of the first month after your start date
• Flexible time off
• Generous parental leave and some fun fringe perks!

What This Job Offers

• Job Type: Full-time
• Career Level: Director