Director, HEOR - Rare Tumor

Merck • Boston, MA

1d

About The Position

As the US Health Economics & Outcomes Research (HEOR) lead for a rare tumor asset, you'll generate rigorous medical evidence to support clinical strategy and inform access decisions by US population health decision-makers. This role involves developing comprehensive value evidence strategies, leading real-world evidence research programs, characterizing disease burden and real-world outcomes, building and validating economic models, creating evidence-focused materials for population health stakeholders, supporting field medical communications, representing HEOR across cross-functional workstreams, synthesizing insights, publishing scientific findings, and managing the research portfolio. You will be part of a diverse, inclusive, and flexible working culture, presenting great opportunities for personal development and career advancement.

Requirements

• Advanced degree (MS or PhD) in Health Economics, Epidemiology, Public Health, Pharmacy, or a closely related field
• 7+ years of HEOR experience in pharmaceutical, biotechnology, population health, or consulting
• Demonstrated hands-on experience in real-world evidence study design and execution
• Proven ability to develop and validate decision-analytic economic models (cost-effectiveness and budget impact)
• Strong understanding of how population health organizations, integrated delivery systems, and formulary decision-makers evaluate evidence and make coverage/access decisions
• Established track record of publishing peer-reviewed HEOR research in medical and scientific journals
• Ability to travel 10%

Nice To Haves

• Track record of developing and executing HEOR strategies within a pharmaceutical company environment, with demonstrated ability to align evidence generation with medical objectives
• Experience in rare disease or oncology, with familiarity of unique clinical challenges, unmet medical needs, and evidence requirements in these areas
• Knowledge of AI and digital solutions applied to evidence synthesis, literature review automation, or health economic modeling workflows

Responsibilities

• Developing comprehensive value evidence strategies — design and execute systematic literature reviews, real-world evidence (RWE) studies, and patient-reported outcomes (PRO) research to build a robust clinical evidence base
• Leading real-world evidence research programs — design observational study protocols, develop Statistical Analysis Plans (SAPs), oversee execution, and produce final reports that meet the highest methodological standards
• Characterizing disease burden and real-world outcomes — lead epidemiological and database analyses to understand patient populations, treatment patterns, and real-world clinical outcomes that inform access decisions
• Building and validating economic models — develop cost-effectiveness and budget impact models grounded in real-world clinical data to quantify value for population health decision-makers
• Creating evidence-focused materials for population health stakeholders — lead development of AMCP Dossiers, health economics briefs, and supporting documentation that translate HEOR findings into formats addressing the evidence and economic evaluation needs of population health decision-makers and formulary committees
• Supporting field medical communications — partner with field medical to translate complex HEOR findings into clear, scientifically sound materials for health system audiences
• Representing HEOR across cross-functional workstreams — collaborate with medical and market access teams to align on evidence strategy, timelines, and deliverables; serve as the HEOR voice in integrated product workstreams
• Synthesizing insights — integrate insights from access stakeholders, clinical experts, and published literature to continuously strengthen and refine the clinical evidence narrative
• Publishing scientific findings — drive peer-reviewed manuscript publication and conference abstracts to establish clinical credibility and contribute to the scientific literature
• Managing the research portfolio — oversee multiple concurrent HEOR projects, external research partnerships, and budgets to deliver high-quality evidence on time and within scope

Benefits

• health insurance
• paid time off (PTO)
• retirement contributions
• other perquisites

What This Job Offers

• Job Type: Full-time
• Career Level: Director