Director - Diagnostic Execution (Oncology Translational Medicine)

GSK • Upper Providence, PA

5d

About The Position

The Director of Diagnostic Execution provides operational leadership for diagnostic activities across GSK’s oncology Antibody Drug Conjugate (ADC) portfolio. The role manages a team of Diagnostic Delivery Leads and is accountable for executing biomarker and diagnostic strategies, overseeing external testing partners, and delivering diagnostic milestones in support of clinical development, regulatory submissions, and diagnostic approvals.

Reporting to the Senior Director, Head of Diagnostic Execution, the Director ensures diagnostic activities meet quality, timeline, budget, and regulatory requirements and supports successful drug-diagnostic co-development. The role works across GSK’s Oncology Translational Medicine function and collaborates with groups including Clinical Development, Clinical Biomarkers, Diagnostic Strategy, Regulatory, Clinical Operations, Quality, Procurement, Data Management, Human Biological Sample Management, external CROs, and diagnostic partners.

The role may be based in Stevenage, UK, or Upper Providence, USA. For a successful applicant based in Stevenage, the role will temporarily be based there before the company’s planned relocation to Cambridge, UK, currently proposed for early 2029. GSK describes an agile working culture and invites candidates to discuss flexibility with the hiring team.

Requirements

• Relevant degree-level education, for example in life sciences.
• Previous line-management experience.
• Relevant experience or knowledge of oncology diagnostic development, implementation, and operational delivery.
• Experience managing vendor relationships, such as external laboratories and diagnostic vendors.
• Strong knowledge of biomarker-driven drug development, precision medicine, and global clinical development processes.
• Proficiency with digital tools including Excel, PowerPoint, Word, SharePoint, and Teams.
• Experience leveraging AI or digital technologies to improve efficiency or insights.

Nice To Haves

• Advanced relevant scientific degree, such as an M.S. or PhD.
• Experience supporting Antibody Drug Conjugate (ADC) development programs.
• Experience in companion diagnostic development and drug-diagnostic co-development.
• Knowledge of global In Vitro Diagnostic Medical Device Regulation (IVDR) and companion diagnostic device regulatory requirements, including interactions with health authorities.
• Experience supporting regulatory submissions, inspections, and audits.

Responsibilities

• Manage operational delivery of biomarker and diagnostic activities for patient selection or stratification across the ADC portfolio.
• Align therapeutic development plans with diagnostic deliverables and oversee diagnostic timelines, budgets, assay performance metrics, risks, and mitigation plans.
• Provide operational leadership for diagnostic programs from assay development through regulatory approval.
• Partner with Diagnostic leads, Clinical Development, Regulatory Affairs, and diagnostic manufacturers to support drug-diagnostic co-development.
• Lead relationships with external parties, including laboratories, CROs, central laboratories, and diagnostic manufacturers.
• Oversee vendor selection, contracting, governance, performance management, and quality compliance.
• Support successful global deployment of diagnostic assays and achievement of operational performance.
• Drive operational excellence, continuous improvement, inspection readiness, and compliance with GCP, GDPR, and global regulatory requirements.

What This Job Offers

• Job Type: Full-time
• Career Level: Director