Crystallization Scientist (Contract)

Vertex Pharmaceuticals • Boston, MA

2d • $60 - $63 • Onsite

About The Position

Vertex is seeking a talented individual to join our Engineering and Materials Sciences group in Boston, MA on a temporary contract basis. Engineering and Materials Sciences at Vertex plays a vital role in bridging the gap between new pharmaceutical discoveries and commercial products. Engineers at Vertex work in multidisciplinary scientific teams to bring basic medical discoveries to patients and physicians by applying fundamental chemistry and chemical engineering principles to new products, processes, and development technologies. The successful candidate will be a highly productive, results-oriented individual, able to generate and implement original ideas and solutions that contribute materially to the success and development of drug substance candidates. Strong communication, organization, and planning skills and a high level of technical aptitude and creativity are required for success in this position.

Requirements

• MS/BS degree with 2 - 5 years of pharmaceutical industry experience.
• Degrees with a life science concentration required, with a preference for concentrations in chemical engineering or chemistry.
• Knowledge and experience in API process development and scale up, in particular small molecule crystallization and particle engineering operations.
• A demonstrated understanding and working knowledge of chemistry and chemical engineering fundamentals; applied kinetics, thermodynamics, and transport fundamentals; as well as familiarity with modern laboratory instrumentation (HPLC, GC, FTIR, Raman, FBRM, DSC, TGA, XRPD, etc) and common laboratory automation tools.
• Experience with statistical design of experiments; QbD concepts; and familiarity with common physical property and process modeling tools (Aspen, Dynochem, Matlab, etc.).
• The ability to successfully interact and collaborate within an interdisciplinary team environment comprised of organic, physical, and analytical chemists, project team members, and manufacturing personnel.
• Proven communication (verbal and written) and interpersonal skills.

Responsibilities

• Supporting drug substance process development on a laboratory/bench scale, and in particular, developing and demonstrating early fit-for-purpose API crystallizations leading to commercially viable API particle forming processes.
• These would include the development of crystallization, isolation, drying, size reduction and other particle engineering operations.

Benefits

• compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency partner upon offer.
• eligible for overtime pay, in accordance with federal and state requirements

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level