2027 Co-op Analytical & Bioanalytical Sciences

Regeneron Pharmaceuticals•Hawthorne, CA

1d•$18 - $51•Onsite

About The Position

Regeneron is currently seeking multiple 2027 Co-ops in Analytical & Bioanalytical Sciences to join our Analytical and Biological Mass Spectrometry (ABMS), Assay Development, and R&D Chemistry teams. These teams develop and apply analytical, bioanalytical, and mass spectrometry-based methods to characterize therapeutic proteins, bioconjugates, and other complex biotherapeutics. These positions offer the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Requirements

Must be enrolled in, or accepted to, an academic program pursuing an Undergraduate or Graduate degree (and be returning to school the semester following the position or graduating after the position)
Must be able to commit to 40 hours per week from January-August, May/June-December, or August-December

Nice To Haves

Demonstrated leadership in areas such as campus activities, clubs, sports, current or previous work, or within the community preferred
Cumulative GPA of 3.0 or higher preferred

Responsibilities

Develop and run liquid chromatography-mass spectrometry (LC-MS) and mass spectrometry imaging (MSI) methods to characterize therapeutic proteins, bioconjugates, and biomarkers
Apply mass spectrometry fragmentation techniques, including collision-induced dissociation (CID) and electron-based dissociation (ExD), to characterize conjugated payloads
Use capillary electrophoresis-mass spectrometry (CE-MS) and imaged capillary isoelectric focusing (iCIEF) to characterize protein charge variants
Build reference databases and spectral libraries, and process and interpret mass spectrometry data to validate molecular structures
Run high-throughput proteomics workflows using data-independent acquisition (DIA) methods and perform database searching with false discovery rate (FDR) control
Develop and evaluate platform immunoassays, including enzyme-linked immunosorbent assay (ELISA) and western blot methods, to support preclinical and clinical bioanalytical studies
Support the development and purification of antibody-drug conjugates (ADCs) using multiple conjugation chemistries, chromatography, and peptide mapping techniques, and compare platform performance across different bioconjugate modalities
Document experimental procedures and results, and present findings to the broader analytical sciences team