Clinical Scientist (CONSULTANT)

Entrada Therapeutics • Boston, MA

1d • Remote

About The Position

Entrada Therapeutics is seeking a highly motivated and experienced clinical researcher to support clinical development across all phases. Reporting to the Executive Director, Clinical Development, the Clinical Scientist will provide strategic guidance and hands-on support for clinical trial strategies in Duchenne muscular dystrophy, using Entrada’s EEV technology. The role focuses on rigorous clinical data review and improving the quality of life of people affected by rare neuromuscular disorders.

This U.S.-based remote consultant position is expected to require 40 hours per week. The role requires travel to Entrada Therapeutics’ Boston headquarters at least quarterly, and preference is given to candidates based in New England.

Requirements

• Ph.D., PharmD, MD, nursing degree, or clinical master’s degree in a scientifically relevant field.
• At least 6 years of clinical development experience in the biotechnology or pharmaceutical industry.
• Proven understanding of clinical development processes sufficient to serve as a subject matter expert for Phase 1–3 clinical studies.
• Experience identifying trends and developing risk-mitigation strategies in partnership with Medical teams within clinical studies.
• Demonstrated experience designing and executing clinical trials, with a strong understanding of GCP/ICH guidelines and regulatory expectations.
• Proficiency with Microsoft Suite and innovative data review tools, such as patient profiles and report-generating tools.
• Self-motivation and a demonstrated ability to deliver assigned tasks according to timelines.
• Demonstrated creative problem-solving and ability to learn.
• Ability to interpret complex data and communicate clearly with scientific and non-scientific stakeholders.
• Strong data analysis, data visualization, and communication skills, including writing clear, accurate, concise documents, constructing informative figures, and presenting to diverse audiences.
• Adaptability and willingness to take on new challenges in an innovative, collaborative, fast-paced, mission-driven environment.

Nice To Haves

• Experience in rare disease and/or neuromuscular disease is strongly preferred.
• New England-based candidates are preferred.

Responsibilities

• Support interpretation of clinical data and prepare high-quality summaries and insights for regulatory filings, publications, and scientific communications.
• Collaborate with Medical Directors, Clinical Operations, Data Management, Biostatistics, and Business Operations to support execution across clinical phases.
• Partner with Medical Directors to lead or support authoring selected sections of clinical study reports.
• Conduct real-time data review, identify safety and efficacy trends, assess protocol compliance, review protocol deviations, and escalate issues to Medical Monitors as appropriate.
• Identify scientific or clinical quality issues for discussion with investigators and study sites, coordinating with the study team and GCP quality team for escalations as needed.
• Consult on study-specific case report form design and author relevant sections of CRF completion guidelines; ensure CRFs align with study requirements during user acceptance testing.
• Conduct safety and efficacy reviews for Data Monitoring Committee meetings with the Medical Director and other internal stakeholders, analyzing trends within and across programs.
• Collaborate with Business Operations and Data Management to lead development and innovation of the department’s clinical data technology access, retention, and visualization strategy.
• Support innovation and strategy for integrating new tools and technologies into Phase 1–3 clinical studies.

What This Job Offers

• Career Level: Mid Level
• Education Level: Ph.D. or professional degree