Clinical Scientist (CONSULTANT)
Entrada Therapeutics•Boston, MA
•Remote
About The Position
Entrada Therapeutics is seeking a highly motivated, experienced clinical researcher to support clinical development across all phases. Reporting to the Executive Director, Clinical Development, the Clinical Scientist will provide strategic and hands-on support for the design, development, and implementation of clinical-trial strategies in Duchenne muscular dystrophy using Entrada’s EEV technology. The role emphasizes scientific rigor, clinical data review, and improving quality of life for people and families affected by rare neuromuscular disorders. This US-based remote consultant position is expected to require 40 hours per week and at least quarterly travel to Entrada Therapeutics’ headquarters in Boston, Massachusetts. Preference is given to candidates based in New England.
Requirements
- Ph.D., PharmD, MD, nursing degree, or clinical master’s degree in a scientifically relevant field.
- At least 6 years of clinical development experience in the biotechnology or pharmaceutical industry.
- Proven understanding of clinical development processes sufficient to serve as a subject matter expert for Phase 1–3 clinical studies.
- Experience identifying trends and developing risk-mitigation strategies in clinical studies in partnership with Medical teams.
- Demonstrated experience in clinical-trial design and execution, and a strong understanding of GCP/ICH guidelines and regulatory expectations.
- Proficiency with Microsoft Office tools and innovative data-review tools, such as patient profiles and report-generating tools.
- Self-motivated, with demonstrated success delivering assigned work according to timelines.
- Creative problem-solving skills and demonstrated ability to learn.
- Ability to interpret complex data and communicate clearly with scientific and non-scientific stakeholders.
- Strong data analysis, data visualization, and communication skills, including writing clear, accurate, concise documents, creating informative figures, and presenting to diverse audiences.
- Ability and desire to work in an innovative, collaborative, fast-paced, mission-driven environment and adapt to new challenges.
- Availability for an expected 40 hours per week and minimum quarterly travel to the Boston headquarters.
Nice To Haves
- Experience in rare disease and/or neuromuscular disease.
- Based in New England.
Responsibilities
- Interpret clinical data and produce high-quality summaries and insights for regulatory filings, publications, and scientific communications.
- Collaborate with Medical Directors, Clinical Operations, Data Management, Biostatistics, and Business Operations to support execution across clinical phases.
- Partner with Medical Directors to lead or support authoring selected sections of clinical study reports.
- Conduct real-time data review, identify safety and efficacy trends, assess protocol compliance, review protocol deviations, and escalate issues to Medical Monitors when appropriate.
- Identify scientific or clinical quality issues for discussion with principal investigators and study sites, coordinating with study teams and GCP quality colleagues on escalations as needed.
- Consult on study-specific case report form design and author relevant sections of CRF completion guidelines; ensure CRFs align with study requirements during user acceptance testing.
- Perform safety and efficacy reviews in preparation for Data Monitoring Committee meetings with Medical Directors and other internal stakeholders, analyzing trends within and across programs.
- Collaborate with Business Operations and Data Management to develop and innovate the department’s clinical data technology access, retention, and visualization strategy to support trend identification across programs.
- Support innovation and strategy for integrating new tools and technologies into Phase 1–3 clinical studies.
