Clinical Research Nurse Coordinator - Duke Cancer Institute

Duke Careers•Durham, NC

1d•$64,966 - $104,996•Onsite

About The Position

You will provide leadership and coordination for multiple, complex oncology clinical trials—including investigational products (IP)—within the Duke Cancer Institute’s Brain Tumor Clinical Research Program (BTC). You’ll collaborate with the Oncology Clinical Research Unit (CRU), Principal Investigators (PIs), sponsors, and study teams to ensure feasibility, compliance, and participant-centered care. Daily, you will recruit and consent participants, conduct study visits, maintain regulatory documentation, and troubleshoot challenges to keep studies on track. Your work spans operations, site management, communication, data integrity, leadership, and ethics. If you thrive in complex neuro-oncology research, enjoy mentoring others, and want to advance breakthrough therapies for brain tumor patients, this role is for you. Join a mission-driven team within the Duke Cancer Institute’s Brain Tumor Clinical Research Program, where discovery, collaboration, and patient-centered care drive everything we do. You will work alongside leading investigators, research nurses, coordinators, and data experts focused on advancing therapies for patients with brain tumors. You’ll find robust professional development and mentorship opportunities, the chance to contribute to scientific presentations and publications, and a culture committed to inclusion and excellence.

Requirements

Graduation from an accredited BSN or Associate Degree in Nursing or Nursing Diploma program
Registered nurses without a BSN must enroll within two years and complete within seven years of start date
Current or compact RN licensure in North Carolina
BLS required
Maintain active NCBON status and hospital/unit competencies
Minimum of 12 months of appropriate clinical nursing experience
On-call: Overnight and/or weekend call for Convection-Enhanced Delivery (CED) infusions
Clinical competencies: Ambulatory medication administration, medication education and management, adult chemotherapy administration, basic dysrhythmia review, lab result review, adverse event assessment, and patient education
Ability to interact effectively with multidisciplinary teams and support patient compliance
Maintain Duke and project-specific training and certification requirements
Follow SOPs, regulations, and protocol requirements governing clinical research

Nice To Haves

Oncology and/or clinical research experience
Familiarity with EDC systems, investigational product handling, and Good Clinical Practice (GCP)
Experience coordinating multi-stakeholder studies and supporting site initiation/closeout

Responsibilities

Provide leadership and coordination for multiple, complex oncology clinical trials—including investigational products (IP)—within the Duke Cancer Institute’s Brain Tumor Clinical Research Program (BTC)
Collaborate with the Oncology Clinical Research Unit (CRU), Principal Investigators (PIs), sponsors, and study teams to ensure feasibility, compliance, and participant-centered care
Recruit and consent participants
Conduct study visits
Maintain regulatory documentation
Troubleshoot challenges to keep studies on track
Direct study operations for multiple complex neuro-oncology trials, including feasibility assessments, recruitment and retention strategies, informed consent, scheduling, and execution of participant visits
Coordinate site management activities (initiation through closeout)
Maintain regulatory binders and study-level documentation
Manage delegation of authority logs
Record and report adverse events (AEs)
Ensure compliance with institutional policies and SOPs
Serve as the primary liaison among sponsors, PIs, CRU, monitors, and study personnel
Communicate clearly and escalate issues appropriately to drive timely resolution
Ensure high-quality data capture in EDC systems
Recognize and troubleshoot data issues
Uphold data security and provenance standards and support query resolution
Partner with finance teams on study payments, participant care expense workflows, and budget development
Monitor financial milestones and assist with study budget closeouts
Provide RN-level clinical support aligned with protocol (e.g., ambulatory medication administration, adult chemotherapy administration, adverse event assessment, laboratory review, patient education, and CED infusion call coverage)
Lead and mentor colleagues
Actively participate in team meetings, committees, task forces, and ad hoc groups
Contribute to scientific presentations and publications
Model research ethics: clearly communicate the distinction between clinical care and research activities to staff and participants
Summarize and clarify applicable professional guidelines and codes of ethics