Clinical Research Manager

UCSF•San Francisco, CA

3d•$121,900 - $277,100•Onsite

About The Position

The Research Program Manager serves as the central operational authority for projects within the Boxer Lab’s clinical research portfolio, leading coordination of internal and external teams across a large multi-institutional research network to support efficient execution of three concurrent NIH-funded clinical research studies (observational and multi-site clinical trials) focused on neurodegenerative diseases. This role operates with a high degree of autonomy and is responsible for directing complex study operations across 50+ clinical sites, overseeing multidisciplinary teams spanning multiple institutions, and ensuring alignment with broader program objectives. Key functions include, but are not limited to: Study Operations Management: Lead day-to-day operations of multiple clinical studies, ensuring adherence with study goals, timelines, and regulatory requirements. Team Leadership and Supervision: Directly supervise project management and administrative staff; provide guidance and operational support to research coordinators; manage coordination with external project managers and functional teams to support aligned and effective study execution. Resource and Workflow Coordination: Allocate resources across projects, establish priorities, and implement processes to support efficient and effective study execution. Financial Oversight: Partner with finance teams to develop and maintain budget tracking tools, monitor study expenditures, and support financial planning activities for three mutli-million dollar NIH studies. HR and Administrative Functions: Support recruitment, hiring, onboarding, and training of study and lab personnel, and contribute to maintaining a productive team environment. In addition to supervising two direct reports within the Boxer Lab, the Research Program Manager oversees coordination and collaboration across multidisciplinary teams spanning multiple institutions and functional areas, including the following: BEYONDD (Observational Study; seven clinical sites): USC-ATRI Team: Project management, data management, and regulatory staff supporting study operations and compliance UCSF Study Team: Site investigators, research coordinators, and study staff supporting remote and on-site participant recruitment and data collection; finance analysts managing invoice processing, site and vendor payments, and overall study budget tracking Mount Sinai Team: Site investigators, research coordinators, and study staff conducting remote and on-site participant recruitment and data collection Clinical Site Teams: Site investigators, research coordinators, and study staff conducting on-site participant data collection Vendors: Mobile phlebotomy services on a national scale and laboratory services supporting sample processing and analysis; biobanking and sample distribution; biomarker assay and data coordination; online study portal development, participant recruitment, and engagement support ATP (Clinical Trial; 78 sites across the US): USC-ATRI Team: Central coordination of multi-site trial operations, including project management, data management, regulatory oversight, clinical and medical monitoring, site support, vendor management, financial oversight, and biomarker analysis UCSF Study Team: Site investigators, research coordinators, and study staff conducting participant recruitment, study visits, and data collection; finance analysts managing invoice processing, site and vendor payments, and overall study budget tracking Clinical Site Teams: Site investigators, research coordinators, and study staff executing protocol implementation and on-site participant data collection across participating sites Industry Partners: External partners providing study drug and supporting study coordination, protocol development, and other aspects of overall trial operations Vendors: Imaging services (MRI and PET), central laboratory services, ECG systems, interactive response technology (IRT), central pharmacy, and electronic trial master file (eTMF) systems PTP (Clinical Trial; 50 sites across North America): USC-ATRI Team: Central coordination of multi-site trial operations, including project management, data management, regulatory oversight, clinical and medical monitoring, site support, vendor management, financial oversight, and biomarker analysis UCSF Study Team: Site investigators, research coordinators, and study staff conducting participant recruitment, study visits, and data collection; finance analysts managing invoice processing, site and vendor payments, and overall study budget tracking Clinical Site Teams: Site investigators, research coordinators, and study staff executing protocol implementation and on-site participant data collection across participating sites Industry Partners: External partners providing study drug and supporting study coordination, protocol development, and other aspects of overall trial operations Vendors: Imaging services (MRI), central laboratory services, ECG systems, IRT, central pharmacy, and eTMF systems This role involves providing both direct supervision and functional oversight across a broad network of clinical research professionals and cross-functional teams spanning multiple studies, institutions, and externally funded programs. The Research Program Manager ensures alignment across internal and external partners, maintains efficient and compliant study operations, and supports financial oversight in coordination with finance teams to ensure responsible management of study budgets. This role also upholds regulatory and ethical standards for research involving human subjects. Effective leadership in this role is critical to supporting high-quality data generation, operational consistency, and the successful execution of complex, multi-site NIH-funded studies.

Requirements

Central coordination of multi-site trial operations, including project management, data management, regulatory oversight, clinical and medical monitoring, site support, vendor management, financial oversight, and biomarker analysis
Site investigators, research coordinators, and study staff conducting participant recruitment, study visits, and data collection; finance analysts managing invoice processing, site and vendor payments, and overall study budget tracking
Site investigators, research coordinators, and study staff executing protocol implementation and on-site participant data collection across participating sites
External partners providing study drug and supporting study coordination, protocol development, and other aspects of overall trial operations
Imaging services (MRI and PET), central laboratory services, ECG systems, interactive response technology (IRT), central pharmacy, and electronic trial master file (eTMF) systems
Imaging services (MRI), central laboratory services, ECG systems, IRT, central pharmacy, and eTMF systems
Mobile phlebotomy services on a national scale and laboratory services supporting sample processing and analysis; biobanking and sample distribution; biomarker assay and data coordination; online study portal development, participant recruitment, and engagement support

Responsibilities

Lead day-to-day operations of multiple clinical studies, ensuring adherence with study goals, timelines, and regulatory requirements.
Directly supervise project management and administrative staff; provide guidance and operational support to research coordinators; manage coordination with external project managers and functional teams to support aligned and effective study execution.
Allocate resources across projects, establish priorities, and implement processes to support efficient and effective study execution.
Partner with finance teams to develop and maintain budget tracking tools, monitor study expenditures, and support financial planning activities for three mutli-million dollar NIH studies.
Support recruitment, hiring, onboarding, and training of study and lab personnel, and contribute to maintaining a productive team environment.
Ensures alignment across internal and external partners, maintains efficient and compliant study operations, and supports financial oversight in coordination with finance teams to ensure responsible management of study budgets.
Upholds regulatory and ethical standards for research involving human subjects.