Clinical Research Manager II

Minneapolis heart institute foundation•Minneapolis, MN

2d•$125,000 - $135,000

About The Position

At Minneapolis Heart Institute Foundation (MHIF), your work supports patient-centered care and helps advance cardiovascular research and education. As a Clinical Research Manager II (CRM II), you will do more than oversee research operations—you will provide strategic leadership, build high-performing teams, and strengthen the partnerships and programs that help change and save lives. At Minneapolis Heart Institute Foundation, we believe our people are our greatest asset and our culture is what sets us apart. Every role contributes to advancing cardiovascular care through research, education, and trusted partnerships, and every employee plays an important role in improving lives around the world. We are committed to fostering a collaborative, innovative, and mission-driven workplace where people feel valued, supported, and empowered to grow. The Clinical Research Manager II (CRM II) provides advanced managerial and strategic leadership for large, complex clinical research and education portfolios across multiple domains. This role partners closely with Principal Investigators, research teams, executive leadership, physicians, and industry collaborators to shape portfolio strategy, optimize resources, and advance organizational priorities. The CRM II leads enterprise-wide initiatives, drives cross-functional collaboration and integration, mentors research staff and other Clinical Research Managers, and may oversee shared services or multiple enterprise-level functions. This role balances day-to-day operational oversight with long-term planning, financial stewardship, innovation, and external relationship management.

Requirements

Bachelor’s degree in life sciences, healthcare, business, or a related field required
Minimum of 5 years of progressive experience in clinical research people management or related leadership roles.
Demonstrated experience managing complex clinical research and education portfolios.
Proven success in project management, strategic planning, team leadership, and cross-functional collaboration.
Experience securing external funding and building strategic partnerships with industry or other external stakeholders.
Strong business acumen, financial planning skills, and ability to manage resources across complex portfolios.
Experience leading enterprise-wide projects, multidisciplinary teams, or multiple functional areas.
Strong written, verbal, and presentation communication skills, with the ability to engage diverse internal and external stakeholders.
Advanced problem-solving, organizational, relationship-management, and decision-making abilities.
Commitment to professional development, innovation, compliance, and external representation.

Nice To Haves

master’s degree or higher preferred

Responsibilities

Oversee large, complex clinical research and education portfolios across multiple domains.
Partner with Principal Investigators and organizational leaders to influence portfolio strategy, long-term planning, and innovation.
Ensure research programs align with MHIF’s long-term vision, organizational goals, and standards of quality and compliance.
Lead strategic planning, resource utilization, and resource allocation for complex portfolios.
Monitor operational performance, address advanced issues, and implement solutions that strengthen efficiency, engagement, and outcomes.
Support the financial health of assigned portfolios through sound business judgment, planning, and oversight.
Maintain awareness of applicable clinical research regulatory requirements and compliance standards.
Lead one or more enterprise-wide projects and initiatives with broad organizational impact.
Drive cross-functional collaboration, strategic integration, and alignment across research programs and operational functions.
Oversee shared services teams or other functional groups in support of organizational initiatives, as assigned.
May expand to oversee multiple enterprise-level functions and lead integration across programs.
Sponsor and influence projects that advance innovation, optimization, and collaboration across research specialties.
Collaborate with executive leadership to identify opportunities, address organizational priorities, and support sustainable growth.
Provide direct supervision and leadership for research staff and may lead cross-functional teams as portfolio needs expand.
Build engaged, high-performing teams through clear expectations, accountability, coaching, and performance management.
Mentor research staff and other Clinical Research Managers, fostering professional development, succession readiness, and talent growth.
Lead multidisciplinary teams and create a culture of collaboration, trust, continuous improvement, and shared accountability.
Champion effective team utilization and engagement across complex research portfolios.
Secure and build strategic partnerships with industry and other external collaborators.
Manage complex relationships with leading industry partners through proactive communication, advanced troubleshooting, and effective problem resolution.
Represent MHIF externally with physicians, industry partners, and other stakeholders as appropriate.
Identify and pursue opportunities to strengthen funding strategy, research partnerships, and organizational visibility.
Support external representation that advances MHIF’s research, education, and mission-driven priorities.