Clinical Research Coordinator - Duke Cancer Institute

Duke Careers•Durham, NC

22h•Onsite

About The Position

The Duke Cancer Institute (DCI) is seeking a Clinical Research Coordinator to play a critical, hands-on role in supporting an operationally complex research study within the Cancer Control and Population Sciences Clinical Research Program (CCPS). This position is housed within the Oncology Clinical Research Unit (CRU) and supports high-impact cancer research that directly engages adult participants through electronic consent, surveys, and biospecimen collection. In this role, you will provide leadership and coordination across all phases of study operations—recruitment, participant engagement, regulatory compliance, data integrity, and collaboration with investigators and sponsors. You will be deeply involved in day-to-day study execution while also helping identify process improvements and resolving operational challenges. If you enjoy balancing detailed coordination work with meaningful participant interaction and collaborative teamwork, this role offers an opportunity to make a direct impact on cancer research at Duke. This position will support the YOGI Study, a cutting-edge research initiative focused on gastrointestinal health and young-onset colorectal cancer. The study’s multi-pathway design, evolving IRB activity, repeated participant engagement, and biospecimen collection create a dynamic learning environment where your organizational skills, problem-solving abilities, and research expertise will be fully utilized and continuously developed.

Requirements

Completion of an Associate’s degree
Two years of relevant research experience
Completion of the DOCR North Carolina state-approved Clinical Research Apprenticeship program may substitute for one year of experience
Ability to effectively use standard computing software and web-based applications (e.g., Microsoft Office products and internet browsers)
Ability to meet and maintain Duke and project-specific training and certification requirements

Nice To Haves

Experience with human subjects research, including informed consent, confidentiality, and adherence to IRB-approved protocols
Strong participant-facing communication skills, including conducting outreach and follow-up via phone and email using standardized scripts
Experience managing complex operational tracking workflows, including monitoring participant status across multiple study pathways
Advanced knowledge or experience building and maintaining databases using REDCap or similar data capture systems
Familiarity with clinical research management systems such as OnCore, eREG, Epic/EMR, or other EDC platforms

Responsibilities

Coordinate and manage study operations by implementing recruitment and retention strategies, evaluating enrollment feasibility, maintaining participant engagement, and identifying barriers to participation while proposing and implementing solutions across the study lifecycle.
Recruit, screen, consent, and support participants by working closely with the Principal Investigator and study team; independently conduct and document consent, schedule and conduct study visits, manage repeated participant outreach and follow-up, and ensure accurate tracking of participant progress across multiple participation pathways.
Ensure regulatory compliance and study integrity by maintaining regulatory binders, enrollment logs, and system documentation; recording and promptly reporting adverse events; assisting with Delegation of Authority Logs, COI documentation, Data Safety Monitoring Plans, and Duke Research Data Lifecycle requirements.
Manage and protect study data by accurately entering data into EDC systems, identifying and resolving data discrepancies, investigating missing or incomplete documentation, and ensuring compliance with institutional policies related to data security, provenance, and confidentiality.
Serve as a key communication and leadership resource by acting as the primary liaison among sponsors, investigators, and study personnel; escalating issues appropriately; supporting onboarding and training of research staff; sharing research updates; and contributing to continuous improvement of research processes.