(Senior Manager / Associate Director) Clinical Operations

Capable Labs • San Francisco, CA

5d • Onsite

About The Position

We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a strong work ethic. In an early-stage environment, we value people who can bring clarity to open-ended problems, take ownership of the next steps, and follow through with energy. Capable Labs is a place for ambitious, high-integrity people who want to become dramatically better. You will be surrounded by people who care intensely about the work, get close feedback from the people making scientific and company-defining decisions, and have room to own increasingly important problems. We believe excellent work should be met with meaningful reward, ownership, and trust. Responsibility is earned through contribution, not title alone: anyone who demonstrates the judgment, rigor, and follow-through to move important work forward can earn meaningful scope. About the Role You will own the operational execution of Capable’s clinical studies, turning study plans into well-run trials and decision-grade human data. Working directly with our founders, scientists, clinicians, regulatory advisors, investigators, sites, and vendors, you will anticipate bottlenecks, drive clear ownership, and keep complex external work moving on time and within scope.

Requirements

• A track record of leading multiple clinical trials from site activation through execution, data delivery, and closeout; experience helping advance a therapy toward approval or market is especially valuable.
• Strong clinical-operations judgment and the ability to identify the few issues most likely to delay or weaken a study.
• Excellent organization and follow-through across many external parties, timelines, and handoffs.
• Strong relationship-building skills and a high bar for investigators, sites, and vendors.
• Experience evaluating and negotiating vendor scopes, budgets, and timelines.
• Comfort operating with high ownership in a fast-moving, early-stage environment.

Responsibilities

• Lead clinical studies from site activation through execution, data delivery, and closeout.
• Identify, evaluate, and manage trial sites, laboratories, manufacturers, pharmacies, IRBs, and other vendors required to run each study.
• Negotiate scopes, budgets, timelines, deliverables, and operating expectations with external partners.
• Build strong working relationships with investigators, site coordinators, vendors, and subject-matter experts.
• Anticipate and resolve operational bottlenecks involving contracting, enrollment, site communication, sample handling, data lag, vendor handoffs, or protocol ambiguity.
• Work with internal and external scientific and clinical partners to design studies that produce clear, decision-grade human data.
• Create practical operating plans, track risks and dependencies, and ensure that decisions and next steps have clear owners.

Benefits

• Generous equity options.
• Compensation will depend on the skills, experience, and scope of impact you bring.
• $500+ monthly wellness budget for training, supplements, coaching, recovery, or other tools that help you perform at your best.
• Medical, dental, and vision coverage options, with Capable covering 100% of the base policy.
• HSA, FSA, and 401K plans.
• Healthy dinners with the team are provided daily.
• Visa sponsorship where appropriate, including O-1, H-1B, J-1, TN, and other employment-based pathways.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: No Education Listed