Clinical Laboratory Chemist III

TX-HHSC-DSHS-DFPSAustin, TX
Onsite

About The Position

Under limited supervision of the Second-Tier LCMS and Biotinidase Group Manager and the Second-Tier LCMS Screening Team Lead, this role independently performs highly complex tandem mass spectrometry (MS/MS) and liquid chromatography-tandem mass spectrometry analysis on newborn screening dried blood specimens. The position is responsible for monitoring and independently performing specimen preparation, analysis, review of quality control and determination of assay acceptability, data evaluation, result entry, maintenance and troubleshooting of equipment, proper record keeping, and training personnel. The role involves making significant decisions on the accuracy of laboratory tests on human specimens and independently determining and releasing complex results based on Standard Operating Protocols (SOP). Active participation in the safety program is also required.

Requirements

  • Bachelor’s degree in a chemical, biological or clinical laboratory science or medical technology from an accredited institution.
  • Experience with analysis of human samples using complex analytical techniques such as mass spectrometry, liquid chromatography-mass spectrometry required.
  • Knowledge and skill in laboratory, clinical chemistry, quality control, quality assurance, MS/MS and LC-MS/MS principles, techniques, and terminology.
  • Knowledge of method development and validation principles.
  • Knowledge of laboratory safety including sample-handling techniques.
  • Ability to communicate effectively orally and in writing.
  • Ability to follow written and verbal instructions.
  • Ability to interact effectively with staff.
  • Ability to work in harmony with other team members.
  • Ability to work as part of a team adhering to structured deadlines for completion of critical laboratory procedures that are performed in high volume.
  • Ability to follow standard operating procedures and protocols accurately.
  • Ability to keep accurate, detailed records.
  • Ability to use aseptic techniques when working with infectious material.
  • Ability to use, maintain and troubleshoot work area instruments and automated testing equipment.
  • Ability to prepare diagnostic (analytical) reagents and/or controls accurately.
  • Skill and dexterity to manipulate standard laboratory equipment with speed, accuracy and safety.

Nice To Haves

  • Experience with validation and troubleshooting liquid chromatography-tandem mass spectrometry instruments preferred.
  • Ability to lead co-workers by setting a positive work-ethic example.
  • Ability to teach work area procedures to co-workers and guests.

Responsibilities

  • Performs highly complex MS/MS and LC-MS/MS analysis on newborn screening specimens adhering to standard operating protocols.
  • Performs sample extraction and preparation of internal standards and test solutions.
  • Assists with training of NBS Metabolic Branch staff to complete technical procedures.
  • Monitors and completes proper record keeping and documentation involved with analytical testing and specimen flow.
  • Collates and files electronic and raw results according to DSHS record retention policies.
  • Evaluates and interprets highly complex data.
  • Identifies problems with atypical test results consulting with Team Lead or Manager and ensuring final result is captured and reported.
  • Reviews and releases final results.
  • Uses Newborn Screening laboratory information management system.
  • Completes and maintains proper record keeping and documentation involved with data evaluation and interpretation.
  • Performs routine and specialized preventive maintenance of highly complex equipment.
  • Identifies equipment problems, performs troubleshooting and makes routine adjustments as indicated.
  • Performs instrument tuning and post maintenance checks.
  • Monitors and performs calibration verifications of liquid handling and other equipment on a scheduled basis.
  • Completes logs, checklists and other record keeping documentation associated with equipment maintenance and instrument performance.
  • Performs sampling of filter paper specimens, standards, and controls for newborn screening tests adhering to standard operating protocols.
  • Uses technical knowledge to determine specimen acceptability.
  • Prepares dried blood spot control and calibration material.
  • Preserves samples and standards according to standard operating protocol.
  • Promotes workflow through cooperative interaction, reassignment of duties, and teamwork with supervisor, co-workers, and internal and external customers.
  • Initiates and delivers rapid communication of abnormal test results to Clinical Care Coordination staff for same day follow-up.
  • Recognizes delays in completion of specimen testing, result reporting, and other essential functions and notifies the team lead or Manager immediately.
  • Manages assigned work to meet specimen testing, reporting, and other essential functions in a timely manner.
  • Conducts training and tours as assigned.
  • Actively participates in quality control review, proficiency testing, equipment performance documentation, specimen workload tallies and supply inventory to ensure consistently acceptable quality assurance and test performance.
  • Assists in developing procedures for processing specimens to ensure the accuracy of the results and proper handling of specimens.
  • Monitors and performs other duties such as disposing biological and hazardous waste and general housekeeping.
  • Employs safe laboratory practices to protect self and others in the laboratory.
  • Consistently complies with DSHS Laboratory, local, state and federal guidelines to ensure a safe functioning laboratory.
  • Performs other duties not specified in the job description, if necessary, as directed by the Manager or Team Lead.

Benefits

  • Insurance coverage and other benefits available through the State of Texas Group Benefits Plan administered by the Employee Retirement System of Texas (ERS).
  • Hepatitis B and Tetanus/Diphtheria immunizations are provided.
  • Weekend shift differential.
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