Clinical Data Manager - Mississauga, ON

GSK•Mississauga, ON

4d•CA$129,000 - CA$179,000•Hybrid

About The Position

GSK is looking to hire a Clinical Data Manager to join our Data Sciences & Management (DS&M) Team. This is a hybrid role based out of Mississauga, requiring 2–3 business days per week in the office, and reports directly to the Director of Data Management. As a Clinical Data Manager, you will be responsible for leading end-to-end clinical data management activities for one or more clinical studies, ensuring high-quality data delivery, regulatory compliance, and operational excellence. You will partner closely with clinical operations, biostatistics, programming, medical writing, and external vendors to support timely study execution and database delivery. Your ability to manage multiple priorities, communicate effectively, and collaborate across global teams will be critical to success. You will also support process improvements, vendor oversight, and mentoring initiatives while contributing to GSK’s mission to help patients do more, feel better, and live longer.

Requirements

Bachelor’s degree in Life Sciences, Computer Science, Statistics, Health Informatics, or a related field
8+ years of experience in clinical data management or clinical trials within pharmaceutical, biotech, CRO, or academic research settings
Practical experience with electronic data capture (EDC) systems and database build activities
Demonstrated knowledge of Good Clinical Practice (GCP) and regulatory expectations for clinical data management
Experience working with external vendors, Functional Service Providers (FSPs), or outsourced clinical data services
Strong oral and written communication skills in English and the ability to collaborate effectively with global cross-functional teams
Strong analytical, organizational, and problem-solving skills
Ability to manage multiple priorities in a fast-paced and collaborative environment

Nice To Haves

Experience with EDC platforms such as Rave, InForm, Veeva, or similar systems
Familiarity with clinical data standards such as CDISC and experience preparing data for regulatory submissions
Experience leading Data Management activities for Phase II or Phase III clinical studies

Responsibilities

Accountable for end-to-end DS&M study-related activities, ensuring quality delivery aligned to study timelines
Leading the creation and execution of Data Management Plans, including data ingestion, cleaning, reconciliation, database lock, and archival activities
Configuring and reviewing electronic Case Report Forms (eCRFs), electronic Diary Cards, and other clinical outcome assessments
Managing interim and final cleaned database locks and ensuring archival of study databases and DM documentation within the eTMF
Leading sponsor oversight activities for outsourced studies managed through Functional Service Providers (FSPs) or Full-Service Outsourcing (FSO) partners
Providing operational data management input into study protocols, study design, planning activities, timelines, and risk registers
Providing study status updates, reports, feedback, and risk assessments to key stakeholders and study teams
Creating and managing study-level timelines for Data Management deliverables and ensuring adherence to project milestones
Promoting implementation of clinical data standards to improve consistency, efficiency, and productivity
Acting as the primary escalation point for Data Management study issues and resolving operational challenges effectively
Ensuring all Data Management deliverables comply with GSK SOPs, Good Clinical Practice (GCP), and regulatory guidelines
Developing and maintaining strong collaborative relationships with cross-functional teams, global stakeholders, and external vendors
Mentoring junior members of the DS&M team and sharing best practices across studies and teams
Supporting audits, inspections, vendor quality assessments, systems implementation, process improvements, and training initiatives