Chief of Staff

Probably Genetic•San Francisco, CA
•$165,000 - $215,000•Hybrid

About The Position

We are at an inflection point. With a Series B on the horizon and a growing portfolio of partnerships with drug developers and patient advocacy groups, we need a Chief of Staff who can operate as a true right hand to the Founder and CEO — someone who runs toward complexity, brings structure to ambiguity, and holds the highest standards of craft and detail. You will own high-stakes initiatives, manage venture fundraising end-to-end alongside the CEO, and serve as a force multiplier across the leadership team. If you have thrived in fast-moving, dynamic environments and want your work to directly improve patient outcomes, this is the role for you.

Requirements

  • 8+ years of experience, with a strong foundation in management consulting (McKinsey, BCG, Bain, or equivalent) and subsequent operating experience at a high-growth startup
  • Prior experience supporting or managing a fundraising process (Series A>D ideally); demonstrated understanding of investor relations and venture dynamics
  • Track record of operating at the intersection of strategy and execution — you are as comfortable in a boardroom as you are building a process from scratch
  • Experience in healthtech or biotech or track record of operating in highly complex industries
  • Meticulous attention to detail — you catch errors others miss and hold every output to an exceptionally high standard
  • Proven, demonstrable AI literacy — you actively use AI tools (beyond prompting) in your daily workflow and can lead others in doing the same
  • Exceptional written communication — you write with clarity, economy, and impact
  • Skilled at managing multiple shifting priorities without dropping the ball — you thrive in dynamic environments where the roadmap changes week to week
  • High emotional intelligence and leadership presence — you know when to push, when to listen, and how to build trust quickly
  • A collaborative, low-ego operating style — you care about outcomes, not credit
  • A good person. We work with some of the most marginalized populations on the planet and empathy is key
  • Patient-focused and motivated to have a lasting, positive impact on humanity
  • Comfortable in a fast-paced, often ambiguous environment with rapid change
  • Action-oriented and excited to build a company from the ground up

Responsibilities

  • Own the end-to-end venture fundraising due diligence: materials, data room, investor outreach, pipeline management, and follow-through
  • Serve as the primary point of coordination between the CEO and prospective and existing investors
  • Prepare board meeting materials, manage the board cadence, and ensure follow-ups are tracked and closed
  • Draft investor updates, pitch narratives, and other strategic communications with precision and clarity
  • Reduce CEO time on operational overhead by 30%+ by owning recurring processes, decision tracking, and stakeholder communication
  • Lead cross-functional projects that span multiple teams, ensuring clarity of ownership, timelines, and outcomes
  • Identify bottlenecks across the organization and build scalable processes to address them before they become problems
  • Prepare the CEO for key meetings with background briefs, talking points, and follow-up documentation
  • Own end to end preparation and execution for quarterly board meetings and mid-quarter check-ins
  • Draft external communications on behalf of the CEO, including company-wide updates, partner communications, and thought leadership via a variety of social channels
  • Ensure data and messaging is consistent and reflects the company's mission and values by creating a consistent framework for use by CEO and broader Leadership Team

Benefits

  • Fair and equitable compensation with competitive early-stage equity grants
  • Generous Flexible Time off policy, that we actually use
  • Parental Leave Benefits (12 weeks for both birthing and non-birthing)
  • Hybrid, flexible work with high-trust and autonomy
  • A bright, inviting, pet-friendly office in Downtown SF near transit
  • Company-sponsored team lunch every Thursday
  • A “work from anywhere” policy, up to 4 weeks a year
  • Regular team retreats in exciting destinations
  • Health Benefits including medical, dental, vision, therapy, FSA, and 401k
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