Chief of Staff

BridgeBio Pharma•Washington, DC

3h•$175,000 - $190,000•Hybrid

About The Position

The Chief of Staff reports directly to the Chief Regulatory Officer (CRO) of BridgeBio. The Office of the CRO (OCRO) spans four pillars—Regulatory Affairs, Portfolio Strategy & Management, R&D Business Operations, and Policy & Advocacy—and this role sits at the center of all of them. The primary objective is to increase the leverage of the CRO, facilitate interactions and information flow across the OCRO and the broader BridgeBio executive leadership team, prepare materials for company leadership and the Board of Directors, take on key cross-functional strategic initiatives, and serve as a strategic thought partner to the CRO. This role is inherently flexible, taking a central role in whatever is most critical to the OCRO at any given moment. With three NDA submissions before the FDA, a robust pipeline advancing behind them, and a policy and advocacy agenda that is growing in scope and visibility, the OCRO is operating at full throttle. The person in this role will be responsible for organizing, interpreting, and presenting a large volume of complex information—and helping the CRO and OCRO leadership use it to make better, faster decisions. They will help address urgent situations, put out fires, and put in place the processes that allow the OCRO to operate seamlessly across four distinct but deeply interconnected functions.

Requirements

Patient-focused
A clear and structured communicator who distills complexity into concise insights and recommendations—whether the topic is a regulatory strategy, a pipeline tradeoff, an operational challenge, or a policy engagement
Comfortable operating in ambiguity and able to create clarity where none exists
Influential without formal authority, able to align senior stakeholders and drive follow-through across the OCRO’s four pillars and beyond
Highly emotionally intelligent, with a proven ability to handle sensitive information and confidential matters with discretion
Detail-oriented but never losing sight of enterprise-level priorities
Biased toward action, with a strong sense of ownership and accountability
Resilient and adaptable, able to shift gears quickly as priorities evolve across a genuinely wide remit
Passion for delivering life-changing treatment options into the hands of patients
Familiarity with the drug discovery, development, and regulatory approval process
Experience working across at least two of the OCRO’s four pillars—regulatory affairs, portfolio strategy, R&D business operations, or policy and advocacy—in a biopharma or life sciences context
Proven technical and business acumen
Demonstrated ability to solve problems using a structured, analytical approach
Ability to handle multiple projects simultaneously
Comfort working independently and as part of a diverse team
Exceptional written communication and presentation skills
Comfort with ambiguity and a self-starter attitude
Extremely fast learner
Exquisitely detail-oriented
Highly empathetic and emotionally intelligent
3 to 6+ years of relevant business development / operations / strategy experience in biopharma
2 to 3 years of experience in a top-tier professional services firm (e.g., consulting) strongly preferred
Graduate degree preferred

Responsibilities

Help define and lead strategic initiatives across OCRO’s four pillars: Regulatory Affairs, Portfolio Strategy & Management, R&D Business Operations, and Policy & Advocacy
Ensure cross-functional alignment and harmonization of strategy with operational activities across the OCRO and with other functions and affiliates throughout BridgeBio
Organize, interpret, and synthesize complex inputs into clear insights, recommendations, and decision-ready materials, including succinct presentations for the CRO, OCRO leadership, senior executives, external stakeholders, and Board-level forums
Manage the operating rhythm of the Office of the CRO by setting agendas, preparing pre-reads, tracking actions, escalating risks, and driving cross-functional follow-through
Conduct regular reviews of case studies and literature on best practices relevant to the OCRO’s scope
Manage key meetings with senior leaders across BridgeBio
Question assumptions and challenge how things are done across BridgeBio in service of the patient mission
Respond to urgent issues and help coordinate cross-functional efforts
Perform other strategic analyses and projects as needed
True expert in the use of AI tools (Claude, ChatGPT), Excel, and PowerPoint

Benefits

Market-leading compensation
401(k) with employer match
Employee Stock Purchase Program (ESPP)
Pre-tax commuter benefits (transit and parking)
Referral bonus for hired candidates
Subsidized lunch and parking on in-office days
100% employer-paid medical, dental, and vision premiums for you and your dependents
Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)
Fertility & family-forming benefits
Expanded mental health support (therapy and coaching resources)
Hybrid work model with flexibility
Flexible, “take-what-you-need” paid time off and company-paid holidays
Comprehensive paid medical and parental leave to care for yourself and your family
Career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching
We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities