Chief of Staff

Cellular Intelligence • Boston, MA

3d • Hybrid

About The Position

Cellular Intelligence (CI) is an AI-native TechBio company building a universal foundation model of cell signaling to understand, predict, and ultimately control cellular behavior, transforming biology from trial-and-error into an engineering discipline. We take a full-stack approach, generating perturbation data at over 1,000x the efficiency of conventional methods, capturing millions of time-resolved treatment combinations per experiment, and training large-scale models that generalize across contexts to enable rational protocol design for regenerative medicine, context-specific drug effect prediction, and systematic disease modeling. Our founding team includes repeat AI entrepreneur Dr. Micha Breakstone (Chorus.ai, acquired for $575M), the Head of the Fundamental AI Group at MIT, and four professors from Harvard Medical School and the University of Washington, including the Chair of Genetics at Harvard, collectively holding five National Academy memberships. Based in Boston, CI has raised over $60M to date from Khosla Ventures, CZI, SciFi VC, and AMD Ventures, and is rapidly scaling its world-class team. Cellular Intelligence’s Core Values: We show up - fully accountable, all-in, doing whatever it takes We act with urgency - swift, decisive, proactive We support one another - collaborative, helpful, empathetic Location: Based in Boston or Austin (preferably, exceptions can be made) In-person time with the CEO and leadership team as needed, with flexibility to work remote when not in a high-cadence stretch. About the Role: We are hiring a Chief of Staff who functions as the CEO’s delegate and operating partner. This person increases decision velocity, execution quality, and organizational clarity across a fast-scaling AI x Biology company. You will run the CEO operating system, drive the highest-leverage cross-functional initiatives, and own critical executive communication and fundraising execution. The goal is simple: take a large share of the CEO’s load and reliably turn it into results. Our current Chief of Staff is transitioning into an internal operations role as we scale and will support a thoughtful handoff.

Requirements

• We are looking for an outlier. A proven top performer with a track record that is hard to miss.
• Off-the-charts excellence: with clear evidence (rapid progression, repeatedly trusted with the hardest problems, exceptional outcomes)
• High judgment, high ownership: You make good decisions fast, and you finish what you start
• Structured thinker: You can turn ambiguity into a plan, a set of priorities, and a tight operating rhythm
• Elite written communication: You can draft CEO- and board-level memos, investor updates, and narratives that are crisp and persuasive
• Strong executive presence and EQ: You can align scientists, operators, and investors without drama, while holding a high bar
• Bias to action with high standards: You move quickly without creating chaos or rework
• Discretion and integrity: Trusted with confidential investor, personnel, and strategic information
• Travel-ready: Comfortable with a role that may require weekly travel, sometimes on short notice

Nice To Haves

• Deep tech, AI, or biotech experience, with the ability to learn technical concepts fast and communicate them clearly
• Prior experience in a high-growth startup environment (0 to 1, 1 to 10, or fundraising-heavy stages)
• Prior Chief of Staff, GM, or operations leadership experience with direct accountability for outcomes
• Experience working with boards, investors, and senior executives in high-velocity settings

Responsibilities

• Build and run the CEO operating system: priorities, weekly planning, meeting architecture, follow-through, and decision logs
• Own a portfolio of top company initiatives end-to-end: especially cross-functional work spanning science, data, and operations
• Translate strategy into execution: goals, metrics, resourcing, risk management, and escalation paths that work in real life
• Represent the CEO with judgment: align leaders, unblock tradeoffs, and drive outcomes with clear guardrails
• Own executive communication: board cadence, investor updates, key memos, and high-stakes external messaging
• Drive fundraising execution: narrative, materials, pipeline hygiene, diligence coordination, and post-meeting follow-through
• Raise organizational throughput: tighten planning, accountability, and hiring and onboarding for critical roles

Benefits

• A role with real leverage, trust, and scope, not a coordination job
• Direct partnership with the CEO on the company’s most important decisions and execution
• Significant exposure to fundraising, strategy, and operating at the leadership level
• A path to expand into larger leadership roles as the company scales, based on strength and impact
• Enjoy a competitive salary and benefits package

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Education Level: No Education Listed