Chief Medical Information Officer (CMIO) - Information Solutions

Medical University of South Carolina • Charleston, SC

5d • Onsite

About The Position

The Chief Medical Information Officer (CMIO) serves as the strategic and operational bridge between clinical practice and health information technology, ensuring that digital solutions enable high-quality, safe, and efficient patient care. As a physician leader, the CMIO champions the optimization and adoption of clinical information systems, translates frontline clinical needs into effective technology strategies, and guides system-wide initiatives that advance clinical excellence, provider engagement, and data-driven decision-making. Collaborating with medical staff, operational leaders, IS, quality, and informatics teams, the CMIO plays a critical role in aligning technology investments with organizational goals, regulatory requirements, and the evolving needs of patients and clinicians. This position is a direct report to the Chief Information Officer (CIO), Information Solutions. The position partners with Chief Medical Officer, Chief Nursing Informatics Officer (CNIO), Chief Health Information Officer, Chief Quality Officer, College of Medicine leadership, MUSC Center for Telehealth, MUSC Center for AI, and MUSC Health operational and digital leaders. The Chief Medical Information Officer (CMIO) is MUSC Health’s senior physician informatics executive, accountable for the full spectrum of physician and Advanced Practice Provider (APP) informatics across the enterprise — including the Charleston academic medical center, MUSC Health regional hospitals across South Carolina, ambulatory practices, and affiliated care settings. This role owns the physician experience with clinical technology end-to-end — from change management and major implementations to onboarding, education, and coaching; from relational support with practicing physicians and APPs to deep partnership with physician leaders, College of Medicine faculty, and executive stakeholders. Reporting directly to the CIO, Information Solutions, the CMIO provides direct influence and partnered leadership over Epic and clinical technology strategy, shaping how tools such as clinical decision support, order sets, documentation workflows, and emerging technologies — including AI-enabled and ambient capabilities — are designed, governed, and used to drive outcomes for MUSC Health’s patients and providers. This is a high-trust, high-influence role that blends strategic leadership with hands-on engagement, requiring strong clinical credibility, systems thinking, and exceptional relationship leadership in an academic, research-intensive, and rapidly growing health system. Key Partnerships — University, Research, Telehealth & AI Partner with MUSC University, the College of Medicine, and the research enterprise to drive research enablement directly into care model design and delivery — translating discovery, learning health system insights, and clinical trials infrastructure into the everyday physician and APP workflow. Embed research-informed pathways, clinical decision support, and data capture into Epic and adjacent tools so that academic insights enrich the patient and provider experience at the point of care. Collaborate with MUSC University faculty, department chairs, and research leaders to align informatics investments with the tripartite mission and to ensure clinical technology supports education, training, and translational research alongside care delivery. Work as a strategic partner with the MUSC Center for Telehealth — leveraging MUSC’s national leadership in telehealth — to drive physician and APP adoption of virtual care, hybrid care, and remote patient monitoring models, and to ensure these capabilities are integrated seamlessly into Epic and clinician workflows. Partner with the MUSC Center for AI (and related digital innovation teams) to evaluate, govern, pilot, and scale AI-enabled and ambient technologies — driving responsible technology and digital adoption while ensuring clinical relevance, safety, equity, and measurable value. Co-develop the physician informatics roadmap with Telehealth and AI leadership so that virtual care, ambient documentation, predictive models, and decision-support algorithms reach clinicians as a coherent, well-supported experience rather than as disconnected point solutions. Leadership Scope & Relationships Lead and mentor associate/regional CMIOs, physician informaticists, and physician leadership roles across direct and matrixed structures. Partner closely with: Enterprise Chief Information Officer, Information Solutions (direct report) Chief Medical Officer and physician executive leadership of MUSC Health MUSC University leadership, College of Medicine Dean’s office, department chairs, division leaders, and research enterprise partners MUSC Center for Telehealth leadership and team MUSC Center for AI and digital innovation leadership Information Solutions executive leadership and Epic application teams Chief Nursing Informatics Officer and nursing leadership Quality, Safety, Population Health, and operational leaders across MUSC Health markets Research and academic leaders supporting clinical research informatics needs Why This Role Matters The CMIO sits at the intersection of care delivery, technology, and trust at MUSC Health. As MUSC Health continues to grow across South Carolina and expand its academic, research, and clinical missions, this role is essential to ensuring that clinical technology amplifies — rather than detracts from — the work of physicians and APPs. By translating the voice of the clinician into informatics strategy, partnering with the CIO and Information Solutions teams, and leading enterprise-wide adoption of modern, AI-enabled tools, the CMIO will directly shape the experience of MUSC Health providers and the outcomes delivered to the patients and communities we serve. In close partnership with MUSC University and the research enterprise, the CMIO will help bring research enablement into care model design and delivery — ensuring that discovery and learning are continuously woven into the workflow to enrich the experience of clinicians, learners, and the patients they care for.

Requirements

• MD or DO with active or eligible South Carolina medical licensure (or ability to obtain).
• Minimum of 10 years of frontline clinical experience with deep understanding of physician and APP workflows.
• Minimum of 10 years leading clinical informatics, health IT, or digital transformation initiatives at scale.
• Proven success in physician engagement, change management, and enterprise-wide influence in a complex health system.
• Demonstrated strategic, operational, and financial acumen.
• Proven ability to lead transformation and manage complexity in highly matrixed academic and community settings.
• Excellent communication and listening skills with the ability to engage diverse stakeholders — from frontline clinicians to executive leadership and Board-level audiences.
• Collaborative, problem-solving approach balancing inclusiveness with timely execution.
• Ability to lead teams through change while maintaining focus on mission, performance, and the well-being of providers.
• Commitment to MUSC’s mission of preserving and optimizing human life in South Carolina and beyond, and to advancing equitable, high-quality care.
• Effective stress management.
• Overtime as required.
• Latex-safe environment.

Nice To Haves

• Eligibility for a faculty appointment at the MUSC College of Medicine commensurate with experience is preferred.
• Clinical Informatics board certification (ABPM/ABMS) or equivalent experience.
• Experience leading physician informatics within an Epic environment in a complex, multi-hospital, academic health system.
• Demonstrated leadership in clinical decision support, workflow optimization, ambient/AI-enabled tools, and technology-enabled care models.
• Experience operating across academic, regional, and ambulatory care environments.
• Rotating shifts.
• If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

Responsibilities

• Serves as the strategic and operational bridge between clinical practice and health information technology.
• Champions the optimization and adoption of clinical information systems.
• Translates frontline clinical needs into effective technology strategies.
• Guides system-wide initiatives that advance clinical excellence, provider engagement, and data-driven decision-making.
• Collaborates with medical staff, operational leaders, IS, quality, and informatics teams.
• Plays a critical role in aligning technology investments with organizational goals, regulatory requirements, and the evolving needs of patients and clinicians.
• Owns the physician experience with clinical technology end-to-end — from change management and major implementations to onboarding, education, and coaching; from relational support with practicing physicians and APPs to deep partnership with physician leaders, College of Medicine faculty, and executive stakeholders.
• Provides direct influence and partnered leadership over Epic and clinical technology strategy, shaping how tools such as clinical decision support, order sets, documentation workflows, and emerging technologies — including AI-enabled and ambient capabilities — are designed, governed, and used to drive outcomes for MUSC Health’s patients and providers.
• Drives research enablement directly into care model design and delivery — translating discovery, learning health system insights, and clinical trials infrastructure into the everyday physician and APP workflow.
• Embeds research-informed pathways, clinical decision support, and data capture into Epic and adjacent tools.
• Aligns informatics investments with the tripartite mission and ensures clinical technology supports education, training, and translational research alongside care delivery.
• Drives physician and APP adoption of virtual care, hybrid care, and remote patient monitoring models, and ensures these capabilities are integrated seamlessly into Epic and clinician workflows.
• Evaluates, governs, pilots, and scales AI-enabled and ambient technologies — driving responsible technology and digital adoption while ensuring clinical relevance, safety, equity, and measurable value.
• Co-develops the physician informatics roadmap with Telehealth and AI leadership.
• Leads and mentors associate/regional CMIOs, physician informaticists, and physician leadership roles across direct and matrixed structures.
• Partners closely with Enterprise Chief Information Officer, Information Solutions (direct report), Chief Medical Officer and physician executive leadership of MUSC Health, MUSC University leadership, College of Medicine Dean’s office, department chairs, division leaders, and research enterprise partners, MUSC Center for Telehealth leadership and team, MUSC Center for AI and digital innovation leadership, Information Solutions executive leadership and Epic application teams, Chief Nursing Informatics Officer and nursing leadership, Quality, Safety, Population Health, and operational leaders across MUSC Health markets, and Research and academic leaders supporting clinical research informatics needs.

Benefits

• The Medical University of South Carolina is an Equal Opportunity Employer.
• MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations.
• All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
• Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Education Level: Ph.D. or professional degree