CAR-T Manufacturing Supervisor 1st shift – Sunday to Wednesday, (Sunday to Tuesday bi-weekly)

Johnson & Johnson•Raritan, NJ

1d•Onsite

About The Position

Johnson & Johnson is seeking a CAR-T Manufacturing Supervisor to direct daily production of personalized cell therapy supporting clinical and commercial requirements in a sterile cGMP environment. The supervisor leads a designated processing manufacturing unit—Day 0, Cell Culture, Day 10, or Component Prep—and works with a team on an assigned production shift. The role is based in Raritan, New Jersey, and supports a strategic collaboration between Janssen Biotech and Legend Biotech to develop, manufacture, and commercialize CAR-T cell therapy. The supervisor assigns and guides daily production work, supports manufacturing personnel on the production floor, and ensures tasks are completed in accordance with safety policies, quality systems, and cGMP requirements. The role also supports investigations, operational documentation and change controls, personnel development, process improvement, and cross-functional coordination. Supervisors must be qualified in the process they oversee and may need to participate in production runs during critical situations. If a run extends beyond the shift, the supervisor must remain with the processing unit until batches are complete. This is a first-shift position, generally scheduled from 6 a.m. to 6 p.m. Sunday through Wednesday, with Sunday through Tuesday shifts on alternating weeks. Hours may be adjusted for business needs. Holiday work is required when holidays fall on scheduled shift days. The role may require up to 10% domestic travel, lifting up to 25 pounds, and standing for extended periods. The supervisor must be able to gown in clean-room attire to oversee operations.

Requirements

At least an associate, vocational, technical/trade, or equivalent degree or certificate.
At least 2 years of relevant experience leading in Operations or Manufacturing in a cGMP environment, such as biotech, biopharma, or engineering.
Experience in aseptic manufacturing and aseptic techniques.
Excellent communication and interpersonal skills.
Advanced experience with Microsoft Office tools, including Word, Excel, PowerPoint, Outlook, MS Channels, Teams, and SharePoint.
Advanced computer literacy and ability to work in electronic systems such as Workday, SAP, Atlas, S4Hana, Elims, MES, Binocs, EMS, and scheduling tools.
Ability to gown in clean-room attire—including scrubs, safety glasses, hair net, face mask, clean-room shoes, and Grade B suit—to oversee operations on the production floor.
Ability to work the stated first-shift schedule and holidays that fall on scheduled shift days.
Ability to lift up to 25 pounds and stand for extended periods.
Willingness and ability to travel domestically up to 10% as required.

Nice To Haves

Bachelor’s degree, preferably in Science, Engineering, or a related field.
Experience working in a laboratory as a Lab Technician, Operations Lead, Manufacturing Specialist, or Manufacturing Operator.
Experience in aseptic manufacturing environments, including clean rooms and laboratories.
Operational Excellence or Lean Manufacturing experience, training, or certification.

Responsibilities

Lead and supervise a designated CAR-T processing manufacturing unit: Day 0, Cell Culture, Day 10, or Component Prep.
Lead daily shift operations meetings, assign production tasks, and ensure work is completed successfully and in compliance with requirements.
Guide production-floor personnel and perform production tasks as needed, consistent with safety policies, quality systems, and cGMP requirements.
Support manufacturing investigations; create or revise operational procedures, manufacturing work instructions, master batch records, and forms; and support and handle change controls.
Work with the Operations Manager on production personnel development and provide input on personnel performance.
Build working relationships with Manufacturing, Engineering, and Quality, and serve as the first point of contact for production-floor operators addressing production issues.
Support manufacturing process development and collaborate cross-functionally on continuous improvements and operational efficiencies.
Participate in department projects and manage challenging priorities in a fast-paced, dynamic environment.
Participate in production runs in critical situations and be qualified in the process being overseen.
Remain with the processing unit beyond scheduled shift end when necessary to complete batches.

Benefits

Company consolidated retirement plan (pension) and savings plan (401(k)), subject to plan terms.
Vacation: 120 hours per calendar year, subject to policy and date of hire.
Sick time: 40 hours per calendar year, with specified state-based amounts for Colorado and Washington employees.
Holiday pay, including floating holidays: 13 days per calendar year.
Work, Personal and Family Time: up to 40 hours per calendar year.
Parental Leave: 480 hours within one year of a child’s birth, adoption, or foster-care placement.
Bereavement Leave: 240 hours for an immediate family member and 40 hours for an extended family member per calendar year.
Caregiver Leave: 80 hours in a 52-week rolling period.
Volunteer Leave: 32 hours per calendar year.
Military Spouse Time-Off: 80 hours per calendar year.