Biostatistician II

Mass General Brigham•Somerville, MA

4d•Hybrid

About The Position

Mass General Brigham is hiring a Biostatistician II to conduct research on the discovery and validation of biomarkers for the early detection of cancer. This role involves developing longitudinal biomarker algorithms for early detection and designing and analyzing retrospective and prospective studies to assess the impact of biomarkers and algorithms on early detection. This research is part of the National Cancer Institute’s Early Detection Research Network (EDRN). The Biostatistician II is responsible for collecting data from medical research and analyzing it to draw conclusions or make predictions. They will also develop and execute research studies in collaboration with other statisticians and scientists, and monitor clinical trials to ensure the integrity of the results.

Requirements

Master's Degree in Biostatistics or Statistics required.
Five years of professional experience in statistical analysis and collaborative work in biomedical or clinical research.
Strong background in statistical programming using R and Stan for advanced inference and data visualization.
Strong communication skills including proficiency in written and spoken English.
Excellent attention to detail.
Ability to explain statistical concepts to non-statistical collaborators.
Experience in supporting studies in all phases, from design through publication.
Strong background in statistical programming using SAS or R.

Nice To Haves

Experience with analysis of next generation sequencing (NGS) data, AI methods, machine learning, or deep learning, is an advantage.

Responsibilities

Develop statistical analysis plans for clinical trials, observational studies, and other biomedical research projects.
Conduct statistical analyses of data from all types of studies, including those with complex designs or requiring sophisticated statistical techniques; begin to oversee biostatisticians and/or statistical programmers.
Generate reports of study progress, including reports for data and safety monitoring boards, and assist in the design of these reports.
Develop programs and guide efforts to perform robust data manipulation and error detection to ensure data integrity.
Provide statistical guidance for grants and other funding proposals.
Assist in hiring, onboarding, training, and mentoring statistical programmers and biostatisticians.
Supervise junior biostatisticians performing data validation during studies.
Provide training and mentorship for junior biostatisticians.
Take on departmental administrative or leadership responsibilities.
Optimizing biomarker discovery pipelines.
Building longitudinal algorithms for earlier detection - each subject serving as their own control.
Optimally combining information across biomarkers and across time.
Designing biomarker validation studies.
Performing inference for early detection clinical trials and observational studies.
Developing advanced graphics to support new statistical methods for grant proposals and publications.
Generating reports on study progress.