Biostatistician II

Mass General Brigham•Somerville, MA

2d•Hybrid

About The Position

Mass General Brigham is seeking a Biostatistician II to join MGH Biostatistics. This role will focus on research related to the discovery and validation of biomarkers for early cancer detection, the development of longitudinal biomarker algorithms for early detection, and the design and analysis of retrospective and prospective studies to evaluate the impact of biomarkers and algorithms on early detection. This research is part of the National Cancer Institute’s Early Detection Research Network (EDRN). The Biostatistician II will be responsible for collecting data from medical research and analyzing it to draw conclusions or make predictions. They will also develop and execute research studies in collaboration with other statisticians and scientists, and monitor clinical trials to ensure the integrity of the results.

Requirements

Master's Degree in Biostatistics or Statistics
Five years of professional experience in statistical analysis and collaborative work in biomedical or clinical research
Strong background in statistical programming using R and Stan for advanced inference and data visualization
Strong communication skills including proficiency in written and spoken English
Excellent attention to detail
Ability to explain statistical concepts to non-statistical collaborators
Advanced Statistics/Biostatistics Experience 3-5 years required
Strong background in statistical programming using SAS or R.
Experience in supporting studies in all phases, from design through publication.

Nice To Haves

Experience with analysis of next generation sequencing (NGS) data, AI methods, machine learning, or deep learning, is an advantage

Responsibilities

Develop statistical analysis plans for clinical trials, observational studies, and other biomedical research projects.
Conduct statistical analyses of data from all types of studies, including those with complex designs or requiring sophisticated statistical techniques; begin to oversee biostatisticians and/or statistical programmers.
Generate reports of study progress, including reports for data and safety monitoring boards, and assist in the design of these reports.
Develop programs and guide efforts to perform robust data manipulation and error detection to ensure data integrity.
Provide statistical guidance for grants and other funding proposals.
Assist in hiring, onboarding, training, and mentoring statistical programmers and biostatisticians.
Supervising junior biostatisticians performing data validation during studies
Providing training and mentorship for junior biostatisticians
Take on departmental administrative or leadership responsibilities
Optimizing biomarker discovery pipelines
Building longitudinal algorithms for earlier detection - each subject serving as their own control
Optimally combining information across biomarkers and across time
Designing biomarker validation studies
Performing inference for early detection clinical trials and observational studies
Developing advanced graphics to support new statistical methods for grant proposals and publications
Generating reports on study progress