Biomarker Scientist - LCMS
About The Position
The position will support a Neuroscience Biomarks client team that is responsible for LC-MS-based proteomics to identify and quantify biomarkers associated with neurodegenerative diseases, including Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis. We are looking for a motivated scientist eager to gain hands-on experience in LC-MS proteomics workflows applied to CSF, plasma, and tissue biomarker studies, and to grow their technical skills in a collaborative, fast-moving research environment. Principal responsibilities will include weekly and monthly lab operations tasks (approximately 70% effort) while additional responsibilities will include routine testing (approximately 30% effort).
Requirements
- B.S. in Biochemistry, Molecular Biology, Biotechnology, Immunology, Neuroscience, or related field with at least 2 years of LCMS experience in the pharmaceutical industry including setup, cleaning, and monthly QC runs.
- Demonstrated hands-on experience with biochemistry and molecular biology techniques, including protein sample preparation, Western Blotting, and buffer preparation.
- Ability to follow and troubleshoot established laboratory protocols independently after training, including identifying and escalating reagent, instrument, or assay issues.
Nice To Haves
- Experience with LC-MS in proteomics workflows.
- Familiarity with automated liquid handlers, Thermo Orbitrap instruments, or Sciex triple quadrupole platforms.
- Authorization to work in the United States indefinitely without restriction or sponsorship.
Responsibilities
- Manage lab instruments, consumables, and chemicals/reagents.
- Manage lab supply and reagent inventory, including aliquoting, ordering, and stocking.
- Perform sample management, including sorting, storage, and manifest recording in Benchling (ELN).
- Prepare reagents and solutions for proteomics and biochemistry workflows.
- Coordinate with the facilities team to manage instrument servicing and preventive maintenance schedules.
- Perform biochemistry assays, including sample preparation and Western Blotting using human or animal biospecimen.
- Perform LC-MS support tasks including instrument source cleaning, monthly QC runs, mobile phase and buffer preparation, and sample injection on Thermo Orbitrap and Sciex triple quadrupole platforms.
- Process and analyze data generated from biochemistry and LC-MS assays under scientist supervision and contribute to summarizing and reporting findings.
- Maintain accurate and detailed records in the electronic laboratory notebook (ELN).
Benefits
- Comprehensive medical coverage, dental, and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
- Eligibility for yearly goal-based bonus & merit-based increases
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
