Biologics Formulation Intern
About The Position
Zoetis is seeking a Biologics Formulation Summer Intern to support formulation development and data-driven research for lyophilized drug products. The 10–12-week internship focuses on developing a rapid, non-destructive Near-Infrared (NIR) spectroscopy method and chemometric model to measure moisture content as a Process Analytical Technology (PAT) tool. The intern will prepare samples with varied moisture levels, collect paired Karl Fischer (KF) and NIR data, and develop and evaluate a model such as partial least squares (PLS) regression. The project aims to make moisture analysis faster and more efficient and to support future 100% vial testing and improved lyophilization process development. The position is based in Kalamazoo, Michigan. The intern will conduct laboratory experiments under supervision and document findings, contributing to technical reports, posters or presentations, and analytical-method documentation supporting future PAT implementation.
Requirements
- Currently enrolled in a bachelor's degree program in Pharmaceutical Sciences, Analytical Chemistry, Chemical or Biomedical Engineering, or a related field.
- Experience working in a laboratory setting, operating laboratory equipment, and recording data.
- Comfort working with data using Excel, JMP, or similar tools.
- Detail-oriented, structured, and able to document experimental work.
- Effective communication skills.
Nice To Haves
- Interest in learning lyophilization techniques, PAT, spectroscopy (NIR/IR), and/or analytical methods.
Responsibilities
- Become familiar with and operate freeze-drying/lyophilization equipment and prepare formulations across defined moisture-content targets.
- Perform Karl Fischer (KF) titration and acquire Near-Infrared (NIR) spectra using established sample-handling and laboratory procedures.
- Develop, optimize, and evaluate chemometric models, such as PLS regression, to correlate NIR spectra with KF moisture measurements.
- Process and analyze experimental data, assess model performance, and support method optimization to minimize false-positive and false-negative results.
- Conduct laboratory experiments under supervision and document findings.
- Contribute to technical reports, posters or presentations, and analytical-method documentation supporting future PAT implementation.
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What This Job Offers
Job Type
Full-time
Career Level
Intern
