Bioinformatics Support Analyst

Guidehouse•Rockville, MD

2d•$85,000 - $141,000•Onsite

About The Position

The Bioinformatics Support Analyst provides operational, analytical, and user-facing support for biomedical informatics applications that process genomic and clinical research data at the National Institute of Allergy and Infectious Diseases (NIAID). This role ensures reliable execution of data workflows, supports data quality and system performance, and contributes to continuous improvement through automation, reporting, and collaboration with engineering and scientific teams. The position balances day-to-day operational support with opportunities to learn new research workflows and contribute to their enhancement, develop reporting capabilities, and improve how data-driven applications support research. This is an excellent opportunity for a professional with a bioinformatics background and strong organizational and communication skills to gain exposure to a range of research systems, perform critical data loading and operational support tasks, and engage with users across NIH and the broader scientific community.

Requirements

Bachelor’s degree or higher in bioinformatics, computational biology, biomedical informatics, or a related field
TWO (2) years experience working with bioscientific, genomic, or clinical data in a research or applied setting
Proficiency in Python or similar scripting languages for data processing, analysis, or workflow support
Familiarity with data pipelines, batch processing, and workflow orchestration concepts
Ability to query, analyze, and interpret data using SQL or similar tools
Experience troubleshooting data processing issues and interpreting system logs or cloud-based monitoring tools
Understanding of data quality principles and best practices for handling sensitive data (e.g., PHI/PII)
Experience using version control systems such as Git
Strong organizational, analytical, and problem-solving skills
Clear written and verbal communication skills, with the ability to document processes and explain technical concepts
Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must obtain approved adjudication of their public trust prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred

Nice To Haves

Exposure to multiple bioinformatics domains (e.g., human genomics, microbial genomics, clinical informatics)
Experience with cloud-based platforms or data environments (e.g., AWS, Terra, AnVIL)
Familiarity with workflow management tools (e.g., Snakemake, Nextflow)
Experience developing dashboards or data visualizations using analytics tools
Knowledge of genomic data formats and tools (e.g., CRAM, variant calling pipelines)
Experience supporting or improving scientific or research-focused applications
Understanding of CI/CD practices and software release processes
Experience contributing to workflow or pipeline improvements beyond routine operations
Familiarity with public biomedical or genomic databases (e.g., ClinVar, gnomAD, OMIM)

Responsibilities

Execute, monitor, and optimize routine data workflows supporting bioscientific, genomic, and clinical data processing
Load, validate, and assess data quality across multiple data types, ensuring completeness, accuracy, and consistency
Perform smoke testing and validation during application releases, updates, and pipeline changes
Troubleshoot user, data, and system issues, including workflow failures, data inconsistencies, and application performance concerns
Analyze application usage, data flow, and system performance using queries, logs, and analytics tools to generate actionable insights
Develop and enhance dashboards, reports, and lightweight automation to improve visibility into workflows and system health
Document processes, workflows, and standard operating procedures, contributing to knowledge sharing and operational scalability
Collaborate with engineering and scientific teams to triage bugs, refine requirements, and support enhancements to data workflows and applications
Identify opportunities for workflow optimization, automation, and improved data handling, and contribute to implementation efforts
Communicate system updates, issues, and insights to technical and non-technical stakeholders

Benefits

Medical, Rx, Dental & Vision Insurance
Personal and Family Sick Time & Company Paid Holidays
Parental Leave
401(k) Retirement Plan
Group Term Life and Travel Assistance
Voluntary Life and AD&D Insurance
Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
Transit and Parking Commuter Benefits
Short-Term & Long-Term Disability
Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
Employee Referral Program
Corporate Sponsored Events & Community Outreach
Care.com annual membership
Employee Assistance Program
Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
Position may be eligible for a discretionary variable incentive bonus