Temporary Bioinformatics Pipeline Assistant

University of Louisville•Aurora, CO

About The Position

The Brown Cancer Center Bioinformatics Core is seeking a part-time, temporary worker to help automate existing computational biology pipelines. The position is approximately 10 hours per week and is expected to last approximately six months. Compensation will be commensurate with candidate experience.

Requirements

  • Four or more years of related experience, or an equivalent combination of education and experience.
  • Strong problem-solving skills and attention to detail.
  • Ability to work independently and collaboratively.
  • Good written and verbal communication skills.

Nice To Haves

  • Degree in Computer Science and Engineering.
  • Proficiency in at least one scripting or programming language commonly used in data pipelines, such as Python, R, and/or Bash.
  • Familiarity with Unix/Linux command-line environments.
  • Understanding of software engineering best practices, including version control, modular design, documentation, and testing.
  • Experience with containerization (Docker/Singularity) and/or HPC/cluster computing.
  • Prior exposure to bioinformatics, computational biology, or handling large scientific datasets.

Responsibilities

  • Refactor and automate existing bioinformatics pipelines, including RNA-Seq, DNA-Seq, ChIP-Seq, single-cell, and long-read sequencing workflows, to improve reproducibility and reduce manual steps.
  • Convert ad hoc analysis scripts into modular, parameterized, and well-documented workflows.
  • Set up and maintain automated execution on high-performance computing (HPC) clusters, including job scheduling and dependency management.
  • Add error handling, logging, and basic validation and testing to existing pipelines.
  • Use version control, such as GitHub, to manage code.
  • Communicate progress regularly and troubleshoot issues in coordination with Core members and the Principal Investigator.
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