Bioinformatician A/B

University of Pennsylvania Perelman School of Medicine
•Onsite

About The Position

The Bioinformatician A/B will collaborate with Dr. Logsdon, postdoctoral fellows, and graduate students to develop, implement, and execute computational methods and tools that assess the organization and evolution of human centromeres using long-read sequencing data. The successful candidate will focus on the discovery of genetic and epigenetic variation within human centromeres relevant to health, disease, and their evolution throughout the primate phylogeny. They will also work as part of large sequencing consortia to develop methods to sequence and assemble high-quality reference genomes.

Requirements

  • Bachelor's Degree and 3 to 5 years of experience or equivalent combination of education and experience is required.
  • Master's Degree and 3 to 5 years of experience or equivalent combination of education and experience is required.

Responsibilities

  • Develop and maintain algorithms and computational tools to assess the sequence composition, organization, and epigenetic landscape of centromeres and other complex regions of the genome using data generated from genome-sequencing projects
  • Create tools to manage and analyze long- and short-read sequencing datasets using massively parallel computing infrastructure
  • Develop programs and/or scripts, including graphical visualization software, to facilitate large-scale data mining of the genome as well as genetic, epigenetics, and expression databases
  • Collaborate with postdoctoral and doctoral researchers and work independently on research projects as assigned by the Investigator. The latter will include the preparation of summaries and reports to be included in publications
  • Other duties and responsibilities as assigned
  • Supervise and manage massively parallel computing infrastructure, shared storage, and standalone web and database servers in collaboration with departmental IT staff
  • Deploy and manage shared software and reference resources
  • Guide the work of junior-level programmer analysts and/or computational students as needed

Benefits

  • excellent healthcare
  • tuition benefits for employees and their families
  • generous retirement benefits
  • a wide variety of professional development opportunities
  • supportive work and family benefits
  • a wealth of health and wellness programs and resources
  • comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits
  • flexible spending accounts
  • tuition assistance
  • generous retirement plans
  • Long-Term Care Insurance
  • Wellness and Work-life Resources
  • Professional and Personal Development
  • Discounts and Special Services
  • Flexible Work Hours
  • Penn Home Ownership Services
  • Adoption Assistance
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