Associate Scientist (Dr Pereira's Lab) - Neurology

Mount Sinai Health System•New York, NY

About The Position

The Pereira Laboratory at the Icahn School of Medicine investigates the neurobiology of Alzheimer’s disease, including selective regional and cellular vulnerability to tau pathology and neurodegeneration. The Associate Scientist will support efforts to discover and validate novel therapeutic targets using animal models, postmortem human tissue, iPSCs, and bioinformatics. The role includes conducting and designing research studies, developing research methods and tools, analyzing and communicating findings, and supporting laboratory operations and research initiatives.

Requirements

Ph.D. in Biological Science or a related field.
Three years of experience.
Demonstrated self-motivation, enthusiasm, and scientific rigor.
Ability to work independently at the bench.

Nice To Haves

Extensive experience working with mouse models, including performing stereotaxic injections.
Strong background in molecular and cell biology.
Experience with cell culture, DNA/RNA isolation, cellular fractionation, Western blotting, PCR/qRT-PCR, in situ hybridization, and immunohistochemical labeling.
Strong interest in neurodegeneration.

Responsibilities

Perform in vivo experiments using mouse models, including stereotaxic injections.
Conduct molecular and cell biology experiments to support ongoing research projects.
Perform laboratory techniques including cell culture, DNA/RNA isolation, cellular fractionation, Western blotting, PCR/qRT-PCR, in situ hybridization, and immunohistochemical labeling.
Conduct research to develop methodologies, instrumentation, and procedures for medical applications; analyze data and present findings.
Design and conduct complex research studies, evaluating alternative methods, computational models, and experimental approaches.
Plan and conduct studies investigating human or animal diseases, preventive methods, and potential treatments.
Assist in clinical laboratory operations as needed.
Follow established laboratory safety procedures to prevent contamination and ensure compliance with safety standards.
Provide training and guidance on medical and laboratory procedures to physicians, residents, students, and research staff.
Collaborate with healthcare professionals, researchers, and other stakeholders to support research initiatives and health safety standards.
Develop research tools, techniques, and methodologies to support scientific investigations.
Identify research questions, develop hypotheses, and establish methodologies for evaluating experimental results.
Analyze and interpret research findings and communicate results through scientific publications and presentations.
Develop research proposals and seek support for new and ongoing research activities.
Provide scientific recommendations to support research activities and project objectives.
Perform other related duties.