Associate Scientist (Dr Pereira's Lab) - Neurology

Mount Sinai Health System•New York, NY

About The Position

The Pereira Laboratory at the Icahn School of Medicine investigates the neurobiology of Alzheimer's disease, including selective regional and cellular vulnerability to tau pathology and neurodegeneration. The Associate Scientist will contribute to efforts to discover and validate novel therapeutic targets using animal models, postmortem human tissue, iPSCs, and bioinformatics. The role involves performing in vivo mouse experiments and molecular and cell biology research, designing and conducting complex studies, analyzing and communicating findings, developing research methods and tools, and supporting research proposals and laboratory operations. The Associate Scientist will also train and guide members of the medical and research community and collaborate with healthcare professionals and other stakeholders.

Requirements

  • Ph.D. in Biological Science or a related field.
  • Three years' experience.

Nice To Haves

  • Extensive experience working with mouse models, including performing stereotaxic injections.
  • Strong background in molecular and cell biology.
  • Experience with cell culture, DNA/RNA isolation, cellular fractionation, Western blotting, PCR/qRT-PCR, in situ hybridization, and immunohistochemical labeling.
  • Strong interest in neurodegeneration.
  • Demonstrated self-motivation, enthusiasm, and scientific rigor.
  • Ability to work independently at the bench.

Responsibilities

  • Perform in vivo experiments using mouse models, including stereotaxic injections.
  • Conduct molecular and cell biology experiments to support ongoing research projects.
  • Perform cell culture, DNA/RNA isolation, cellular fractionation, Western blotting, PCR/qRT-PCR, in situ hybridization, and immunohistochemical labeling.
  • Conduct research to develop methodologies, instrumentation, and procedures for medical applications, including analyzing data and presenting findings.
  • Design and conduct complex research studies, evaluating alternative methods, computational models, and experimental approaches.
  • Plan and conduct studies investigating human or animal diseases, preventive methods, and potential treatments.
  • Assist in clinical laboratory operations as needed.
  • Follow established laboratory safety procedures to prevent contamination and ensure compliance with safety standards.
  • Provide training and guidance on medical and laboratory procedures to physicians, residents, students, and research staff.
  • Collaborate with healthcare professionals, researchers, and other stakeholders to support research initiatives and health safety standards.
  • Develop research tools, techniques, and methodologies to support scientific investigations.
  • Identify research questions, develop hypotheses, and establish methodologies for evaluating experimental results.
  • Analyze and interpret research findings and communicate results through scientific publications and presentations.
  • Develop research proposals and seek support for new and ongoing research activities.
  • Provide scientific recommendations to support research activities and project objectives.
  • Perform other related duties.

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What This Job Offers

Job Type

Full-time

Career Level

Mid Level

Education Level

Ph.D. or professional degree

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