Associate Scientist, Product Biochemistry (NMR)

Regeneron Pharmaceuticals • Tarrytown, GA

3d • Onsite

About The Position

Our Product Biochemistry team is seeking a highly motivated Associate to join our dynamic and collaborative group. In this role, you will be responsible for implementing biophysical assessment strategies on different drug modalities such as oligonucleotides, peptides, and small molecule payloads, including collecting and analyzing NMR data, to support research and development efforts. You will play an integral part in technology innovation efforts aimed at enhancing our understanding of therapeutic agents through advanced NMR methodologies. A Typical Day as an Associate Scientist Looks Like: Conduct NMR experiments and analyze data to elucidate the structural and chemical properties of oligonucleotide, peptide, and small molecule candidates. Develop and optimize NMR protocols and methods to support both upstream and downstream research initiatives. Document all analytical work in electronic laboratory notebooks according to defined protocols with accuracy and attention to detail. Communicate experimental findings and data interpretation to supervisors and project teams. Summarize results in a concise format for presentations and regulatory documents. Present findings at group, departmental, and cross-functional meetings. Maintain and troubleshoot instruments and other essential laboratory equipment. Utilize additional analytical methods characterize therapeutic candidates alongside NMR studies, and participate in protein purification/enrichment activities. This Role May Be for You If You Have: Experience in the general operations of a laboratory and the ability to manage and organize scientific data under managerial supervision. Technical competencies in NMR spectroscopy, with hands-on experience in collecting and interpreting NMR data on oligonucleotides, peptides, and small molecules. Experience operating a range of NMR instruments and troubleshooting instrumentation issues. Strong organizational skills and the ability to prioritize multiple tasks in a fast-paced environment. Ability to contribute to lab equipment maintenance and safety to help create a safe, effective and efficient working environment. Familiarity with related analytical techniques such as chromatography or mass spectrometry is a plus. This role requires a Bachelor’s or Master’s degree in Chemistry, Biochemistry, Biophysics, or a related field plus 0-3 yrs+ experience with an emphasis on NMR data collection and analysis of oligonucleotides, peptides, or small molecules. Preference will be given to candidates who have experience working in the biopharmaceutical industry. Excellent oral and written communication skills and evidence of teamwork are required. Experience with SEC-MALS, iCE, CE-SDS, DSC, or general protein purification and chromatography techniques is highly desirable and considered a plus for this role. The ideal candidate must have strong initiative to complete tasks, learn new technologies, and demonstrate a commitment to continuous learning. This role requires the ability to manage multiple priorities in a fast-moving R&D environment, operate effectively both independently and within a collaborative team environment, and communicate clearly, transparently, and in a timely manner with key stakeholders.

Requirements

• Experience in the general operations of a laboratory and the ability to manage and organize scientific data under managerial supervision.
• Technical competencies in NMR spectroscopy, with hands-on experience in collecting and interpreting NMR data on oligonucleotides, peptides, and small molecules.
• Experience operating a range of NMR instruments and troubleshooting instrumentation issues.
• Strong organizational skills and the ability to prioritize multiple tasks in a fast-paced environment.
• Ability to contribute to lab equipment maintenance and safety to help create a safe, effective and efficient working environment.
• This role requires a Bachelor’s or Master’s degree in Chemistry, Biochemistry, Biophysics, or a related field plus 0-3 yrs+ experience with an emphasis on NMR data collection and analysis of oligonucleotides, peptides, or small molecules.
• Excellent oral and written communication skills and evidence of teamwork are required.
• This role requires the ability to manage multiple priorities in a fast-moving R&D environment, operate effectively both independently and within a collaborative team environment, and communicate clearly, transparently, and in a timely manner with key stakeholders.

Nice To Haves

• Familiarity with related analytical techniques such as chromatography or mass spectrometry is a plus.
• Preference will be given to candidates who have experience working in the biopharmaceutical industry.
• Experience with SEC-MALS, iCE, CE-SDS, DSC, or general protein purification and chromatography techniques is highly desirable and considered a plus for this role.
• The ideal candidate must have strong initiative to complete tasks, learn new technologies, and demonstrate a commitment to continuous learning.

Responsibilities

• Conduct NMR experiments and analyze data to elucidate the structural and chemical properties of oligonucleotide, peptide, and small molecule candidates.
• Develop and optimize NMR protocols and methods to support both upstream and downstream research initiatives.
• Document all analytical work in electronic laboratory notebooks according to defined protocols with accuracy and attention to detail.
• Communicate experimental findings and data interpretation to supervisors and project teams.
• Summarize results in a concise format for presentations and regulatory documents.
• Present findings at group, departmental, and cross-functional meetings.
• Maintain and troubleshoot instruments and other essential laboratory equipment.
• Utilize additional analytical methods characterize therapeutic candidates alongside NMR studies, and participate in protein purification/enrichment activities.

Benefits

• We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels!
• For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/.
• For other countries’ specific benefits, please speak to your recruiter.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level