Associate Scientist, Preformulation Sciences (Contractor)

Vividion Therapeutics, Inc•San Diego, CA
•$40 - $50•Onsite

About The Position

Vividion Therapeutics is seeking a highly motivated Associate Scientist, Preformulation Sciences (Contractor) to support formulation development activities for small-molecule drug discovery programs. This hands-on laboratory role is responsible for preparing and characterizing preclinical formulations, performing HPLC-based analytical testing, and conducting routine chemistry laboratory operations. The ideal candidate will possess strong analytical chemistry expertise, including HPLC troubleshooting and method optimization, along with the scientific judgment and critical-thinking skills needed to investigate anomalous results and drive data-based decision-making. Experience with preclinical formulation development is highly desirable.

Requirements

  • Bachelor's degree in Chemistry, Pharmaceutical Sciences, Analytical Chemistry, Biochemistry, or a related scientific discipline.
  • 6+ years of relevant industry experience in analytical chemistry, pharmaceutical sciences, formulation development, or related fields.
  • Demonstrated expertise operating and troubleshooting HPLC systems and supporting analytical method development or optimization.
  • Strong laboratory skills, including accurate weighing, pipetting, solution preparation, and pH measurement.
  • Proven ability to work independently, manage multiple priorities, and maintain high-quality documentation.
  • Strong scientific reasoning, critical-thinking, and problem-solving skills, with the ability to identify, challenge, and interpret unexpected results.

Nice To Haves

  • Experience preparing preclinical formulations for PK, efficacy, toxicology, or related in vivo studies.
  • Experience supporting small-molecule drug discovery or pharmaceutical development programs.
  • Familiarity with formulation stability assessments and physicochemical characterization.
  • Experience working within cross-functional research, DMPK, pharmacology, toxicology, or CMC teams.
  • Knowledge of UPLC, LC-MS, or related analytical techniques.

Responsibilities

  • Independently prepare and characterize preclinical formulations following established protocols.
  • Operate, maintain, troubleshoot, and support development of HPLC analytical methods.
  • Perform quantitative analyses to evaluate formulation concentration, chemical stability, and related analytical attributes.
  • Critically assess analytical and experimental data, investigate unexpected findings, and identify root causes of anomalous results.
  • Perform routine laboratory operations, including accurate weighing of compounds, pH measurement, solution preparation, buffer and mobile phase preparation, and sample handling.
  • Maintain complete and accurate electronic laboratory notebooks and communicate study results, progress, risks, and recommendations to stakeholders.
  • Manage workload and timelines to support agreed-upon study schedules.
  • Coordinate formulation delivery and activities with cross-functional teams, including pharmacology, toxicology, and other research groups.
  • Support laboratory operations through inventory management, supply ordering, material shipments, and general lab organization.
  • Perform additional duties as required

Benefits

  • The hourly pay for this position ranges from $40.00 to $50.00 depending on relevant skills, competencies, experience, and education.
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