Associate Scientist, In Vivo Pharmacology

Bristol Myers Squibb•San Diego, CA

2d•$93,230 - $112,970•Onsite

About The Position

The Pharmacology group within the Protein Homeostasis Thematic Research Center (TRC) at BMS San Diego provides in vivo pharmacology support to discovery teams focused on developing small molecules and biologics for oncology and immune-oncology. As an integral part of discovery programs, the group supports lead identification through in vivo model screening and mechanism-of-action studies, develops and validates animal disease models, identifies pathway biomarkers, and establishes clinically relevant endpoints to assess efficacy. Collaboration with DMPK, Exploratory Toxicology, and Translational Development is central to our work, and we contribute preclinical data to inform clinical development plans. We are seeking a motivated Associate Scientist with broad experience in pharmacology and drug discovery for both small and large molecules. The successful candidate will work collaboratively in a multidisciplinary environment, taking responsibility for experiment design, planning, and execution. Key duties include interpreting and presenting in vivo data, conducting sample and endpoint analyses (ELISA, Western blot, Jess, qPCR, IHC), and preparing protocols and reports. The role requires independent work, technical expertise, and contributions to project decisions. Strong communication, self-motivation, innovation, flexibility, and teamwork are essential.

Requirements

Bachelor’s Degree
2+ years of academic and / or industry experience with oncology models

Nice To Haves

Experience in mammalian cell culture
Experience in the development of syngeneic and xenograft cancer models
Proficient in animal handling, dosing (PO, IP, IV, and SC), tumor cell inoculation, data collection and analysis
Hands-on experience in small animal surgeries, necropsy and tissue and blood collection
Hands-on experience in evaluating small molecules in animal models
Experience with small animal imaging modalities (e.g., Xenogen, ultrasound etc.) is a plus.
Skilled in Western blots, ELISA, MesoScale, IHC, flow cytometry, RNA/DNA extraction, and PCR
Proficient in Excel, Word, PowerPoint, FlowJo, GraphPad Prism, and Studylog
Excellent interpersonal, communication, presentation, collaboration, and organizational skills
Detail-oriented, focused, and able to deliver high-quality data efficiently

Responsibilities

Develop disease models for oncology and immune-oncology
Independently design and execute in vivo efficacy and PK/PD experiments to identify drug candidates
Analyze and interpret data accurately, reporting findings to supervisors and colleagues
Troubleshoot routine issues and recommend solutions
Evaluate endpoints from in vivo studies using Western blots, mesoscale, qPCR, etc.
Write precise protocols and technical reports
Present data to multidisciplinary discovery teams
Collaborate with cross-functional team members

Benefits

Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Paid Time Off
US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
unlimited paid sick time
up to 2 paid volunteer days per year
summer hours flexibility
leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs
an annual Global Shutdown between Christmas and New Years Day.