Associate Scientist II, MSAT

Strand Therapeutics•Boston, MA

1d•Onsite

About The Position

Strand Therapeutics is seeking a highly motivated and innovative Associate Scientist II of MSAT to join a small but extremely productive team. This role will involve supporting the execution, continuous improvement, and maturation of Strand’s preclinical and clinical-stage manufacturing processes. The ideal candidate will have experience supporting gene and/or cell therapies manufacturing and will be a strategic thinker with a leadership presence. This opportunity offers the ability to work in a matrix-based environment and contribute to the future strategy of the company.

Requirements

B.S. or Advanced Degree in Biochemistry, Chemical Engineering or related field, with 2+ years of working experience in RNA and/or LNP process improvement, manufacturing and/or optimization at a biotech.
Experience collecting, analyzing, and interpreting experimental data to evaluate process performance and support technical conclusions.
Experience with process development, scale-up, technology transfer, manufacturing support, and process troubleshooting.
Strong technical documentation and communication skills.
Ability to generate and maintain clear and detailed laboratory records, and present experimental designs, data interpretation, and conclusions to cross-functional groups.

Nice To Haves

Experience contributing to process characterization or later-stage development activities is a plus.
Experience optimizing and troubleshooting enzymatic reactions, chromatographic purification, TFF, and other filtration methods for biologics.
Familiarity with ÄKTA systems and UNICORN control software is preferred.
Hands-on experience with RNA and/or LNP production processes and respective standard analytical methods (UV-Vis Spectroscopy, Gel Electrophoresis, ELISA, DLS, RiboGreen, etc.) strongly preferred.

Responsibilities

Support the execution, continuous improvement, and maturation of Strand’s preclinical and clinical-stage manufacturing processes.
Perform lab-scale RNA and lipid nanoparticle production and analytical testing to evaluate process improvements, troubleshoot technology transfer and manufacturing challenges, improve process robustness, and support process scale-up.
Author technical protocols and reports documenting experimental procedures, results, and conclusions.
Collaborate with Process Development, Analytical Development, Automation, and Quality teams to advance Strand’s manufacturing programs.
Partner with external technical counterparts to support ongoing tech transfer and manufacturing activities.