Associate Scientist II, MSAT

Strand Therapeutics•Boston, MA

7h•$81,000 - $89,000•Onsite

About The Position

Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company. We are looking for a highly motivated and innovative candidate for the role of Associate Scientist II of MSAT. The expectation is that the Associate Scientist II will have experience prior supporting preclinical and clinical-stage manufacturing processes within the gene and/or cell therapies space. Reporting to the Senior Scientist of MSAT, the right candidate will be a strategic thinker that brings a leadership presence and enthusiasm for Strand along with a desire to conquer new challenges.

Requirements

B.S. or Advanced Degree in Biochemistry, Chemical Engineering or related field, with 2+ years of working experience in RNA and/or LNP process improvement, manufacturing and/or optimization at a biotech.
Experience collecting, analyzing, and interpreting experimental data to evaluate process performance and support technical conclusions.
Experience with process development, scale-up, technology transfer, manufacturing support, and process troubleshooting.
Experience optimizing and troubleshooting enzymatic reactions, chromatographic purification, TFF, and other filtration methods for biologics.
Strong technical documentation and communication skills. Ability to generate and maintain clear and detailed laboratory records, and present experimental designs, data interpretation, and conclusions to cross-functional groups.

Nice To Haves

Experience contributing to process characterization or later-stage development activities is a plus.
Familiarity with ÄKTA systems and UNICORN control software is preferred.
Hands-on experience with RNA and/or LNP production processes and respective standard analytical methods (UV-Vis Spectroscopy, Gel Electrophoresis, ELISA, DLS, RiboGreen, etc.) strongly preferred.

Responsibilities

Support the execution, continuous improvement, and maturation of Strand’s preclinical and clinical-stage manufacturing processes.
Perform lab-scale RNA and lipid nanoparticle production and analytical testing to evaluate process improvements, troubleshoot technology transfer and manufacturing challenges, improve process robustness, and support process scale-up.
Author technical protocols and reports documenting experimental procedures, results, and conclusions.
Collaborate with Process Development, Analytical Development, Automation, and Quality teams to advance Strand’s manufacturing programs.
Partner with external technical counterparts to support ongoing tech transfer and manufacturing activities.