Associate Researcher I - Hematology & Medical Oncology
About The Position
The researcher will work in the laboratory of Hanna Irie and will be engaged in translational breast cancer research projects focused on regulators of growth, survival and drug resistance, as well as the tumor microenvironment. The researcher will use a broad range of approaches (genetic, cell biological and in vivo modeling) to understand how breast cancers, particularly triple negative breast cancers, resist chemotherapy treatments and metastasize. The projects also examine novel mechanisms that contribute to the growth and metastases of triple negative breast cancers. The researcher will utilize patient-derived xenograft models of breast cancer and organoid cultures to screen and validate novel therapeutic strategies in collaboration with chemical biologists. The researcher will also study how the immune microenvironment regulates response of breast and other cancers to chemotherapy/targeted therapies. The researcher will be expected to design and conduct experiments, be responsible for accurate record keeping and contribute to overall maintenance of the laboratory. The goals are to develop and validate novel therapeutics targeting novel oncogenes in breast cancer models.
Requirements
- Translational breast cancer research projects focused on regulators of growth, survival and drug resistance, as well as the tumor microenvironment
- Use a broad range of approaches (genetic, cell biological and in vivo modeling) to understand how breast cancers, particularly triple negative breast cancers, resist chemotherapy treatments and metastasize
- Examine novel mechanisms that contribute to the growth and metastases of triple negative breast cancers
- Utilize patient-derived xenograft models of breast cancer and organoid cultures to screen and validate novel therapeutic strategies in collaboration with chemical biologists
- Study how the immune microenvironment regulates response of breast and other cancers to chemotherapy/targeted therapies
Responsibilities
- Design and conduct experiments
- Be responsible for accurate record keeping
- Contribute to overall maintenance of the laboratory
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
No Education Listed
