Associate Research Scientist

Thermo Fisher Scientific•Collegeville, PA

1d•Onsite

About The Position

Thermo Fisher Scientific is seeking a Cellular & Molecular Biologist for its Target Validation department within Target Discovery. The team supports cell line engineering and target validation across discovery programs involving CRISPR-based gene editing, cell culture, molecular biology, assay execution, and data analysis. The role contributes to multiple programs and disease areas in a collaborative, fast-paced environment. The position is fully onsite at a customer site in Collegeville, Pennsylvania. The scientist designs and executes experiments to generate reagents and data that support program decisions, and delivers genome-edited cell reagents to cross-functional project teams. The role reports to a laboratory supervisor. Applicants must be authorized to work in the United States without sponsorship and pass a comprehensive background check, including drug screening. Relocation assistance is not provided.

Requirements

Previous experience providing relevant knowledge, skills, and abilities comparable to 4 or more years; or a master's degree and comparable experience of 2 or more years; or a PhD.
Must be legally authorized to work in the United States without sponsorship.
Must be able to pass a comprehensive background check, including drug screening.
Ability to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
Ability to work upright and stationary and/or standing for typical working hours.
Ability to lift and move objects up to 25 pounds.
Ability to work in non-traditional work environments and use and learn standard office equipment and technology proficiently.
Ability to perform successfully under pressure while prioritizing and handling multiple projects or activities.

Nice To Haves

Strong practical knowledge of cell biology.
Expertise in advanced cell culture, including cell lines, primary cells, co-culture and other complex cellular models, and iPSCs.
Experience building advanced, translational cellular models and assays combined with genome editing to support drug discovery.
Working knowledge of genetics, target validation, compound screening, and assay development.
Documented experience or publications demonstrating technology development in genome editing or related emerging fields.
Experience with functional genomics techniques, including Sanger, Nanopore, PacBio, or Illumina sequencing; genotyping; primer/probe design; qRT-PCR; and ddPCR.
Proficiency with SnapGene, Benchling, or equivalent software.
Ability to lead multidisciplinary teams effectively to drive decision-making.
Programming and bioinformatics skills for sequencing data analysis.
Broad scientific understanding across therapeutic areas such as oncology, immunology, infectious diseases, metabolic diseases, and neurology.
Ability to manage and prioritize multiple concurrent tasks and evaluate competing scientific strategies in parallel.
Demonstrated relationship-building, flexible thinking, and ability to enable and drive change.
An equivalent combination of appropriate education, training, and/or directly related experience may be considered.

Responsibilities

Independently plan, execute, analyze, and deliver genome-edited cell reagents to multiple cross-functional project teams.
Engineer cell lines, primary cells, iPSCs, and iPSC-derived cells to build translationally relevant cellular models for assay development.
Identify, develop, and adopt new technologies and editing strategies to improve workflow efficiency and capability.
Contribute scientific insight to program strategy and planning within multiple matrix teams, supporting data-driven decision-making that advances drug discovery.
Comply with GSK R&D data integrity practices, ethics codes, standards, and safety training and procedures.