Associate Principal Scientist, Large Molecule Bioanalytical

IQVIA • Indianapolis, IN

2d • $83,000 - $173,000

About The Position

IQVIA Laboratories is seeking an Associate Principal Scientist to provide technical leadership for complex large-molecule bioanalytical method development and laboratory studies. The role collaborates with clients and cross-functional teams to deliver scientifically rigorous solutions supporting drug development programs. It is based in Indiana.

The scientist serves as Primary Investigator on client studies, conducts laboratory work, and communicates study progress and results. The role also leads complex technical projects, evaluates and implements methods and technologies, interprets experimental findings, prepares study documentation, and guides or mentors junior scientific staff. Work is performed in accordance with applicable laboratory standards, regulatory requirements, SOPs, and good documentation practices.

Requirements

• Master’s degree in a science field, plus 8 or more years of experience, or an equivalent combination of education, training, and experience in a bioanalytical laboratory environment.
• Experience with antibodies, antibody-drug conjugates, or oligonucleotide conjugates containing payloads such as ASOs, PMOs, or siRNA.
• Experience with large-molecule bioanalytical techniques such as mass spectrometry, CE-SDS, SDS-PAGE, BCA, SEC-HPLC, and UV-visible spectroscopy.
• Experience evaluating the stability, potency, efficacy, and purity of therapeutic candidates used in in vitro or in vivo studies.
• Ability to independently manage multiple complex projects, priorities, and experimental deliverables.
• Strong scientific writing, presentation, data interpretation, and client communication skills.
• Ability to collaborate effectively across departments and contribute to multidisciplinary scientific discussions.
• Advanced proficiency with Microsoft Excel, including statistical analysis, as well as PowerPoint, Word, and instrument-supporting software.
• Working knowledge of applicable laboratory regulatory requirements, SOPs, and good documentation practices.
• Demonstrated leadership, mentoring, organization, interpersonal effectiveness, and time management skills.
• An equivalent combination of education, training, and experience may be accepted in lieu of a degree.

Responsibilities

• Serve as Primary Investigator on client studies, conduct laboratory work, and communicate study progress and results.
• Design and execute complex bioanalytical method development experiments.
• Evaluate and implement new methods, technologies, and instrumentation for client programs.
• Prepare technical reports, study proposals, and protocols, including documentation that may support FDA submissions.
• Lead multiple complex technical projects and guide or mentor junior scientific staff.
• Analyze and interpret experimental findings, including statistical analysis, in accordance with laboratory standards.
• Maintain laboratory notebooks, equipment, and study documentation in compliance with applicable regulatory standards, SOPs, and good documentation practices.
• Collaborate across functions to deliver studies, deploy methods, and provide project updates to team leads and project managers.

Benefits

• The company describes integrated benefits programs and resources addressing employees’ and their families’ physical, mental and emotional, financial, and social well-being.
• Health and welfare benefits may be offered, depending on the position.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior